Lim Seon Hwa, Kim Yon Hee, Yim Ga Won, Nam Eun Ji, Kim Young Tae, Kim Sunghoon
Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seoul, Korea.
Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
Obstet Gynecol Sci. 2013 Nov;56(6):412-5. doi: 10.5468/ogs.2013.56.6.412. Epub 2013 Nov 15.
Extra-ovarian yolk sac tumor arising in the omentum is extremely rare. As yolk sac tumor originated from the omentum has been rarely reported, its clinical information is very limited. The authors encountered a case of yolk sac tumor originated from the omentum, and reported the case herein. A 32-year-old woman was presented with developed low abdominal distension for a month. Magnetic resonance imaging findings were suggestive of ovarian malignancy with ascites and peritoneal seeding nodules. Explorative laparotomy was performed and then the findings from frozen biopsy of omentum were suggestive of poorly differentiated tumor though whether it was primary or metastatic was uncertain. Thus, staging laparotomy were performed. Histopathology confirmed that the tumor was a yolk sac tumor of omentum origin. Then, 6 cycles of postoperative adjuvant chemotherapy at intervals of 3 weeks were performed using bleomycin, etoposide, and cisplatin regimen. Four-year outpatient follow-up thereafter showed no relapse.
起源于大网膜的卵巢外卵黄囊瘤极为罕见。由于起源于大网膜的卵黄囊瘤鲜有报道,其临床资料非常有限。作者遇到一例起源于大网膜的卵黄囊瘤,并在此报告该病例。一名32岁女性出现下腹部膨隆1个月。磁共振成像结果提示卵巢恶性肿瘤伴腹水和腹膜种植结节。进行了剖腹探查术,大网膜冰冻活检结果提示为低分化肿瘤,但不确定是原发性还是转移性。因此,进行了分期剖腹手术。组织病理学证实该肿瘤是起源于大网膜的卵黄囊瘤。然后,采用博来霉素、依托泊苷和顺铂方案进行了6个周期的术后辅助化疗,化疗间隔为3周。此后4年的门诊随访显示无复发。