Jones M A, Clement P B, Young R H
Department of Pathology, Maine Medical Center, Portland 04102.
Am J Clin Pathol. 1994 Jan;101(1):42-7. doi: 10.1093/ajcp/101.1.42.
Two yolk sac tumors that arose in the mesentery of the jejunum and the mesentery of the transverse colon of two male patients, aged 2 and 17 years, are reported. Both patients had abdominal masses. The tumors measured 9 and 11 cm in maximum dimension. One of them grew into the bowel lumen. Microscopically, both neoplasms exhibited several of the typical patterns of yolk sac tumor and stained immunohistochemically for alpha-fetoprotein. Both patients received chemotherapy postoperatively and are alive, but follow-up is short. The subject of extragonadal yolk sac tumors is reviewed, and histogenetic implications of their occasional origin in the mesentery is discussed.
本文报告了两名男性患者，年龄分别为2岁和17岁，分别在空肠系膜和横结肠系膜发生的两例卵黄囊瘤。两名患者均有腹部肿块。肿瘤最大直径分别为9厘米和11厘米。其中一个肿瘤向肠腔内生长。显微镜下，这两种肿瘤均呈现出卵黄囊瘤的几种典型形态，并通过免疫组织化学染色检测甲胎蛋白。两名患者术后均接受了化疗，目前仍存活，但随访时间较短。本文对性腺外卵黄囊瘤进行了综述，并讨论了其偶尔起源于系膜的组织发生学意义。
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