Fibrosis of tunica albuginea: complication of long-term intracavernous pharmacological self-injection.

We report 3 cases of penile curvature deformity and fibrosis of the tunica albuginea after long-term self-injection with papaverine hydrochloride and phentolamine mesylate. To our knowledge this complication has not been reported previously. The clinical presentation and possible etiology are discussed.