脂肪源性干细胞辅助自体脂肪移植在乳房修复与重建中的进展
[Advancement of adipose-derived stem cells assisted autologous lipotransfer in breast repair and reconstruction].
作者信息
Tian Chunxiang, Lü Qing
机构信息
Department of Thyroid & Breast Surgery, West China Hospital, Sichuan University, Chengdu Sichuan 610041, PR China.
出版信息
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2013 Oct;27(10):1252-5.
OBJECTIVE
To review the latest progress in the major biological properties of adipose-derived stem cells (ADSCs) and ADSCs assisted autologous lipotransfer in breast repair and reconstruction.
METHODS
Recent literature about ADSCs assisted autologous lipotransfer in breast repair and reconstruction was reviewed.
RESULTS
ADSCs have multipotential differentiation capacity, and they could promote angiogenesis and regulate immune reactions. ADSCs assisted autologous lipotransfer can obtain satisfactory effectiveness in breast repair and reconstruction with few complications, but more studies are needed to confirm the long-term safety.
CONCLUSION
ADSCs assisted autologous lipotransfer has good effectiveness in breast repaired and reconstruction. But further clinical trials are needed to confirm the long-term safety.
目的
综述脂肪来源干细胞（ADSCs）的主要生物学特性以及ADSCs辅助自体脂肪移植在乳房修复与重建中的最新进展。
方法
回顾近期关于ADSCs辅助自体脂肪移植在乳房修复与重建方面的文献。
结果
ADSCs具有多向分化能力，可促进血管生成并调节免疫反应。ADSCs辅助自体脂肪移植在乳房修复与重建中可获得满意效果，并发症较少，但需要更多研究来证实其长期安全性。
结论
ADSCs辅助自体脂肪移植在乳房修复与重建中具有良好效果。但需要进一步的临床试验来证实其长期安全性。
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