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脂肪源性干细胞辅助自体脂肪移植在乳房修复与重建中的进展

[Advancement of adipose-derived stem cells assisted autologous lipotransfer in breast repair and reconstruction].

作者信息

Tian Chunxiang, Lü Qing

机构信息

Department of Thyroid & Breast Surgery, West China Hospital, Sichuan University, Chengdu Sichuan 610041, PR China.

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2013 Oct;27(10):1252-5.

PMID:24397141
Abstract

OBJECTIVE

To review the latest progress in the major biological properties of adipose-derived stem cells (ADSCs) and ADSCs assisted autologous lipotransfer in breast repair and reconstruction.

METHODS

Recent literature about ADSCs assisted autologous lipotransfer in breast repair and reconstruction was reviewed.

RESULTS

ADSCs have multipotential differentiation capacity, and they could promote angiogenesis and regulate immune reactions. ADSCs assisted autologous lipotransfer can obtain satisfactory effectiveness in breast repair and reconstruction with few complications, but more studies are needed to confirm the long-term safety.

CONCLUSION

ADSCs assisted autologous lipotransfer has good effectiveness in breast repaired and reconstruction. But further clinical trials are needed to confirm the long-term safety.

摘要

目的

综述脂肪来源干细胞(ADSCs)的主要生物学特性以及ADSCs辅助自体脂肪移植在乳房修复与重建中的最新进展。

方法

回顾近期关于ADSCs辅助自体脂肪移植在乳房修复与重建方面的文献。

结果

ADSCs具有多向分化能力,可促进血管生成并调节免疫反应。ADSCs辅助自体脂肪移植在乳房修复与重建中可获得满意效果,并发症较少,但需要更多研究来证实其长期安全性。

结论

ADSCs辅助自体脂肪移植在乳房修复与重建中具有良好效果。但需要进一步的临床试验来证实其长期安全性。

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[Advancement of adipose-derived stem cells assisted autologous lipotransfer in breast repair and reconstruction].脂肪源性干细胞辅助自体脂肪移植在乳房修复与重建中的进展
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2013 Oct;27(10):1252-5.
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[Cell-assisted lipotransfer for breast augmentation: a report of 18 patients].[细胞辅助脂肪移植隆乳术:18例患者报告]
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The impact of human adipose tissue-derived stem cells on breast cancer cells: implications for cell-assisted lipotransfers in breast reconstruction.人脂肪组织来源干细胞对乳腺癌细胞的影响:对乳房重建中细胞辅助脂肪移植的启示
Stem Cell Res Ther. 2017 May 25;8(1):121. doi: 10.1186/s13287-017-0579-1.
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Positive Effects of Subdermal Lipotransfer on Pig's Upper Eyelid Skin: Mature Adipocytes or Adipose-Derived Stem Cells Alone Contribute Little and Only Cotransplantation of Them Can Generate Benefits.皮下脂肪移植对猪上睑皮肤的积极作用:单独的成熟脂肪细胞或脂肪来源干细胞作用甚微,只有二者共同移植才能产生益处。
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[Effects of rat allogeneic adipose-derived stem cells on the early neovascularization of autologous fat transplantation].[大鼠异体脂肪间充质干细胞对自体脂肪移植早期血管新生的影响]
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Current perspectives on cell-assisted lipotransfer for breast cancer patients after radiotherapy.细胞辅助脂肪转移在乳腺癌放疗后患者中的应用现状。
World J Surg Oncol. 2023 Apr 17;21(1):133. doi: 10.1186/s12957-023-03010-z.

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