Mazkereth Ram, Miron Eitan, Leibovitch Leah, Kuint Jacob, Strauss Tzipora, Maayan-Metzger Ayala
Department of Neonatology, The Edmond and Lili Safra Children's Hospital, Sheba Medical Center , Ramat-Gan , Israel and.
J Matern Fetal Neonatal Med. 2014 Nov;27(17):1795-9. doi: 10.3109/14767058.2014.880688. Epub 2014 Feb 3.
To evaluate and compare growth parameters (weight, length and head circumference) of discordant preterm twins during the first year of life.
Retrospective data were collected on 78 pairs of >10% discordant preterm twins. Data regarding short-term neonatal outcome were recorded. Growth parameters were recorded at birth and again at 1 year of age, as collected by phone interview.
At 1 year of age, the gap was significantly reduced between the group of smaller twins and the group of larger twins on all the parameters studied. Discordance in weight decreased from a mean of 22% at birth (calculated from the weight of the larger twin) to 8.9%, in length from 6.5% to 2.5% and in head circumference from 5.5% to 1.3% at 1 year of age. While length and head circumference (HC) z-scores improved in both the large and the small siblings, weight z-score decreased significantly among the large twins and decreased mildly among the small twins.
The gaps in growth parameters between the smaller twins of preterm discordant twins and their larger siblings are significantly reduced during the first year of life. The impact of the differential growth patterns between the two siblings should be further evaluated.
评估和比较出生体重不一致的早产双胞胎在出生后第一年的生长参数（体重、身长和头围）。
收集了78对体重差异>10%的早产双胞胎的回顾性数据。记录了短期新生儿结局的数据。通过电话访谈收集出生时及1岁时的生长参数。
在1岁时，在所研究的所有参数上，较小双胞胎组和较大双胞胎组之间的差距显著缩小。体重差异从出生时（根据较大双胞胎的体重计算）的平均22%降至1岁时的8.9%，身长差异从6.5%降至2.5%，头围差异从5.5%降至1.3%。虽然较大和较小的双胞胎的身长和头围z评分均有所改善，但较大双胞胎的体重z评分显著下降，较小双胞胎的体重z评分略有下降。
出生体重不一致的早产双胞胎中较小的双胞胎与其较大的同胞在生长参数上的差距在出生后第一年显著缩小。应进一步评估两个同胞之间不同生长模式的影响。
