花生四烯酸的脂氧合酶代谢产物作为海兔感觉细胞突触前抑制的第二信使。
Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells.
作者信息
Piomelli D, Volterra A, Dale N, Siegelbaum S A, Kandel E R, Schwartz J H, Belardetti F
出版信息
Nature. 1987;328(6125):38-43. doi: 10.1038/328038a0.
DOI:10.1038/328038a0
PMID:2439918
Abstract
Biochemical and biophysical studies on Aplysia sensory neurons indicate that inhibitory responses to the molluscan peptide FMRFamide are mediated by lipoxygenase metabolites of arachidonic acid. These compounds are a new class of second messengers in neurons.
摘要
对海兔感觉神经元的生化和生物物理研究表明，对软体动物肽FMRF酰胺的抑制反应是由花生四烯酸的脂氧合酶代谢产物介导的。这些化合物是神经元中一类新的第二信使。
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