Takayama Yukihisa, Nishie Akihiro, Asayama Yoshiki, Ushijima Yasuhiro, Fujita Nobuhiro, Shimamoto Dai, Yoshiura Takashi, Obara Makoto, Takemura Atsushi, Yoneyama Masami, Honda Hiroshi
Department of Molecular Imaging and Diagnosis, Graduate School of Medical Sciences, Kyushu University, Higashi-ku, Fukuoka City, Fukuoka, Japan.
J Magn Reson Imaging. 2015 Feb;41(2):339-46. doi: 10.1002/jmri.24554. Epub 2014 Jan 8.
To assess the clinical utility of tissue-specific variable refocusing flip-angle (VRFA) turbo-spin echo imaging for three-dimensional T2-weighted imaging (3D-T2WI) of the liver.
Fifty-nine patients were scanned with three types of fat-suppressed T2WI for the comparison: two-dimensional single-shot turbo spin echo T2WI (ssT2WI), 3D-T2WI with tissue-specific VRFA (VISTA-TSV), and 3D-T2WI with low-constant VRFA (VISTA). Qualitatively, artifacts in the left and right lobes of the liver and black-blood effects in the liver were compared using the Wilcoxon signed-rank test with the Bonferroni correction. The detection and correct characterization rates of liver lesions were compared using McNemar's test.
VISTA-TSV showed reduced artifacts in the left and right lobes of the liver compared with VISTA (P < 0.017). The artifacts shown by VISTA-TSV were equivalent to those shown by ssT2WI. The black-blood effects of VISTA-TSV and VISTA were better than that of ssT2WI (P < 0.017). VISTA-TSV showed the best detection and correct characterization rate of liver lesions among the three imaging techniques (P < 0.05).
3D-T2WI with tissue-specific VRFA can reduce artifacts of the liver, sufficiently suppress the signal in blood vessels, and has a potential to improve the detection and correct characterization rates of liver lesions.
评估组织特异性可变重聚焦翻转角（VRFA）涡轮自旋回波成像在肝脏三维T2加权成像（3D-T2WI）中的临床应用价值。
对59例患者进行了三种脂肪抑制T2WI扫描以作比较：二维单次激发涡轮自旋回波T2WI（ssT2WI）、采用组织特异性VRFA的3D-T2WI（VISTA-TSV）以及采用低恒定VRFA的3D-T2WI（VISTA）。定性方面，采用经Bonferroni校正的Wilcoxon符号秩检验比较肝脏左右叶的伪影以及肝脏中的黑血效应。采用McNemar检验比较肝脏病变的检出率和正确特征化率。
与VISTA相比，VISTA-TSV显示肝脏左右叶的伪影减少（P < 0.017）。VISTA-TSV显示的伪影与ssT2WI相当。VISTA-TSV和VISTA的黑血效应优于ssT2WI（P < 0.017）。在三种成像技术中，VISTA-TSV对肝脏病变的检出率和正确特征化率最高（P < 0.05）。
采用组织特异性VRFA的3D-T2WI可减少肝脏伪影，充分抑制血管信号，并有可能提高肝脏病变 的检出率和正确特征化率。
