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支配大鼠胰腺的辣椒素敏感迷走传入神经元。

Capsaicin-sensitive vagal afferent neurons innervating the rat pancreas.

作者信息

Carobi C

出版信息

Neurosci Lett. 1987 Jun 1;77(1):5-9. doi: 10.1016/0304-3940(87)90597-0.

DOI:10.1016/0304-3940(87)90597-0
PMID:2439955
Abstract

The vagal afferent innervation of the rat pancreas was investigated by the use of retrograde axonal transport of horseradish peroxidase (HRP) injected into the pancreas through the common bile duct. Many labeled neuronal somata were found in the right and left nodose ganglia. The size distribution of the labeled neuronal population in the nodose ganglia was examined and compared with that obtained from rats pretreated with capsaicin. In rats treated neonatally with capsaicin the smallest neurons (up to 200 micron2) were completely absent and those belonging to the second and third classes (200-300, 300-400 micron2) were reduced in both vagi.

摘要

通过经胆总管将辣根过氧化物酶(HRP)注入大鼠胰腺,利用逆行轴突运输法研究了大鼠胰腺的迷走神经传入神经支配。在左右结状神经节中发现了许多标记的神经元胞体。检查了结状神经节中标记神经元群体的大小分布,并与用辣椒素预处理的大鼠的分布进行了比较。在新生期用辣椒素处理的大鼠中,最小的神经元(直径达200平方微米)完全缺失,并且在双侧迷走神经中,属于第二和第三类(200 - 300、300 - 400平方微米)的神经元数量减少。

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