Mangal Jed P, Rimland David, Marconi Vincent C
1 Emory University School of Medicine , Atlanta, Georgia .
AIDS Res Hum Retroviruses. 2014 May;30(5):409-15. doi: 10.1089/aid.2013.0232. Epub 2014 Feb 7.
The cascade of HIV care in the United States has become a focus for interventions aimed at improving the success of HIV treatment. The Atlanta VA Medical Center (AVAMC) Infectious Disease Clinic (IDC) is an urban clinic that provides care for over 1,400 people living with HIV (PLHIV) annually. Using data from the HIV Atlanta VA Cohort Study (HAVACS), we modeled the continuum of care in the AVAMC IDC and explored similarities and differences with national models. We conducted a cross-sectional analysis of 1,474 individuals receiving care in the AVAMC IDC. We estimated total PLHIV and defined several categories within the spectrum of HIV care. We then developed the continuum of care using two methodologies. The first required each stage to be a dependent subset of the immediate upstream stage. The second allowed each stage to be independent of upstream stages. Dependent stage categorization estimated that 95.3% of individuals were diagnosed with HIV, 89.8% of individuals were linked to care, 73.0% of individuals were retained in care, 65.9% of individuals were eligible for antiretroviral treatment (ART), 62.8% were prescribed ART, and 52.4% had a suppressed viral load (VL). Independent stage categorization estimated that 83.9% of individuals were prescribed ART and 61.5% had a suppressed VL. Our analyses showed that the AVAMC IDC estimates were significantly better than national estimates at every stage. This may reflect the benefits of a universal healthcare system. We propose the use of independent stages for the continuum as this more accurately represents healthcare utilization.
美国的艾滋病病毒(HIV)治疗连续过程已成为旨在提高HIV治疗成功率的干预措施的重点。亚特兰大退伍军人事务医疗中心(AVAMC)传染病诊所(IDC)是一家城市诊所,每年为1400多名HIV感染者(PLHIV)提供治疗。利用来自HIV亚特兰大退伍军人事务队列研究(HAVACS)的数据,我们对AVAMC IDC的治疗连续过程进行了建模,并探讨了与全国模型的异同。我们对在AVAMC IDC接受治疗的1474名个体进行了横断面分析。我们估算了PLHIV的总数,并在HIV治疗范围内定义了几个类别。然后,我们使用两种方法建立了治疗连续过程。第一种方法要求每个阶段都是紧邻上游阶段的依赖性子集。第二种方法允许每个阶段独立于上游阶段。依赖阶段分类估计,95.3%的个体被诊断出感染HIV,89.8%的个体与治疗机构建立了联系,73.0%的个体持续接受治疗,65.9%的个体符合抗逆转录病毒治疗(ART)条件,62.8% 的个体接受了ART治疗,52.4% 的个体病毒载量(VL)得到抑制。独立阶段分类估计,83.9%的个体接受了ART治疗,61.5%的个体病毒载量得到抑制。我们的分析表明,AVAMC IDC在每个阶段的估计都明显优于全国估计。这可能反映了全民医疗保健系统的益处。我们建议在治疗连续过程中使用独立阶段,因为这能更准确地反映医疗保健的利用情况。