Mishra Manisha, Sawhney Ravindra, Kumar Anil, Bapna Kumar Ramesh, Kohli Vijay, Wasir Harpreet, Trehan Naresh
Department of Cardiaothoracic and Vascular Anesthesiology, Medanta The Medicity, Gurgaon, Haryana, India.
Ann Card Anaesth. 2014 Jan-Mar;17(1):46-51. doi: 10.4103/0971-9784.124141.
The fetal death rate associated with cardiac surgery with cardiopulmonary bypass (CPB) is as high as 9.5-29%. We report continuous monitoring of fetal heart rate and umbilical artery flow-velocity waveforms by transvaginal ultrasonography and their analyses in relation to events of the CPB in two cases in second trimester of pregnancy undergoing mitral valve replacement. Our findings suggest that the transition of circulation from corporeal to extracorporeal is the most important event during surgery; the associated decrease in mean arterial pressure (MAP) at this stage potentially has deleterious effects on the fetus, which get aggravated with the use of vasopressors. We suggest careful management of CPB at this stage, which include partial controlled CPB at initiation and gradual transition to full CPB; this strategy maintains high MAP and avoids the use of vasopressors. Maternal and fetal monitoring can timely recognize the potential problems and provide window for the required treatment.
与体外循环(CPB)心脏手术相关的胎儿死亡率高达9.5%-29%。我们报告了两例妊娠中期接受二尖瓣置换术的患者,通过经阴道超声对胎儿心率和脐动脉血流速度波形进行连续监测,并分析它们与CPB事件的关系。我们的研究结果表明,循环从体内向体外的转变是手术过程中最重要的事件;在此阶段平均动脉压(MAP)的相关下降可能对胎儿产生有害影响,使用血管升压药会使这种影响加剧。我们建议在此阶段对CPB进行仔细管理,包括在开始时采用部分控制性CPB并逐渐过渡到全流量CPB;这种策略可维持较高的MAP并避免使用血管升压药。母婴监测能够及时识别潜在问题并为所需治疗提供契机。