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What is the significance of posttreatment control of HIV infection vis-à-vis functional cure?

作者信息

Vanham Guido, Buvé Anne, Florence Eric, Seguin-Devaux Carole, Sáez-Cirión Asier

机构信息

aVirology Unit, Department of Biomedical Sciences bUnit of Epidemiology and Control of HIV/STD, Department of Public Health cHIV/STD Clinic, Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium dVic Arendt, Sylvie Delhalle, Centre de Recherche Public de la Santé, Luxemburg, Luxemburg eUnité de Régulation des Infections Rétrovirales, Institut Pasteur, Paris, France.

出版信息

AIDS. 2014 Feb 20;28(4):603-5. doi: 10.1097/QAD.0000000000000147.

DOI:10.1097/QAD.0000000000000147
PMID:24401643
Abstract
摘要

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BMJ Open. 2021 Nov 29;11(11):e048582. doi: 10.1136/bmjopen-2020-048582.
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Rapid viral rebound after analytical treatment interruption in patients with very small HIV reservoir and minimal on-going viral transcription.在 HIV 储存量极小且持续病毒转录极少的患者中,分析治疗中断后病毒迅速反弹。
J Int AIDS Soc. 2020 Feb;23(2):e25453. doi: 10.1002/jia2.25453.
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Early Initiation of Antiretroviral Therapy Can Functionally Control Productive HIV-1 Infection in Humanized-BLT Mice.
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J Acquir Immune Defic Syndr. 2015 Aug 15;69(5):519-27. doi: 10.1097/QAI.0000000000000687.