Müller S, Theise H
Z Erkr Atmungsorgane. 1987;168(2):142-8.
To compare two different sources of bird-antigens (intestinal extracts versus serum dilutions) we performed intracutaneous tests in 79 birdkeepers (34 pigeon-, 20 hen- and 25 budgerigar-keepers) and in nonexposed control persons. The bird-exposed persons were divided into 3 groups: 1. Seropositive patients with extrinsic allergic alveolitis (EAA), 2. seropositive persons without any signs of EAA (sensitized asymptomatics), and 3. exposed seronegative healthy persons. The results of the investigation demonstrate that the early skin-reaction (20 minutes after antigen-application) is nonspecific and do not have any diagnostic value. Most of patients with EAA (65.7%) and 29.6% of sensitized asymptomatics developed a positive 6-hour-(Arthus-) reaction with intestinal extracts, whereas in control groups we have not seen any Arthus reaction. Consequently, we recommend the use of intestinal extracts in the diagnostic procedure of EAA.
为比较两种不同来源的鸟类抗原(肠道提取物与血清稀释液),我们对79名鸟类饲养者(34名鸽子饲养者、20名母鸡饲养者和25名虎皮鹦鹉饲养者)以及未接触鸟类的对照人员进行了皮内试验。接触鸟类的人员被分为3组:1. 患有外源性过敏性肺泡炎(EAA)的血清阳性患者;2. 无EAA任何体征的血清阳性人员(致敏无症状者);3. 接触鸟类的血清阴性健康人员。调查结果表明,早期皮肤反应(抗原应用后20分钟)是非特异性的,没有任何诊断价值。大多数EAA患者(65.7%)和29.6%的致敏无症状者对肠道提取物产生了阳性6小时(阿瑟斯)反应,而在对照组中我们未观察到任何阿瑟斯反应。因此,我们建议在EAA的诊断过程中使用肠道提取物。