Supportive and Palliative Care, The Ottawa Hospital Cancer Centre, Ottawa, Ontario, Canada.
Curr Opin Support Palliat Care. 2014 Mar;8(1):70-6. doi: 10.1097/SPC.0000000000000029.
The role of palliative care interventions in patients with nonmetastatic disease is unclear. Locally advanced breast cancer (LABC) is such a diagnosis that presents a platform to examine the relationship of symptom management while patients are receiving treatment with curative intent.
Overwhelming physical and psychological symptoms can affect women with LABC. Fungating lesions at the time of primary presentation remain a major challenge. Treatments specifically for the treatment of fungating lesions using new dressings, topical analgesics, buccal opioids, and old techniques such as larval therapy were explored.
LABC is a complex biosocial disease that requires a collaborative interdisciplinary approach to care.
姑息治疗干预在非转移性疾病患者中的作用尚不清楚。局部晚期乳腺癌（LABC）就是这样一种诊断，它为我们提供了一个平台，来研究在患者接受治愈性治疗的同时，症状管理与治疗效果之间的关系。
晚期乳腺癌患者会出现压倒性的躯体和心理症状。在初次就诊时出现的溃烂性病变仍然是一个主要的挑战。人们探索了一些专门用于治疗溃烂性病变的方法，包括使用新型敷料、局部止痛药、口腔阿片类药物，以及幼虫疗法等旧技术。
LABC 是一种复杂的生物社会疾病，需要采用协作性的多学科方法来进行治疗。
