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放射治疗使乳腺溃疡性病变显著消退

Dramatic Regression of a Fungating Breast Lesion Treated with Radiation Therapy.

作者信息

Gao Robert W, Edlund Shane, Yuan Jianling

机构信息

School of Medicine, University of Minnesota.

Department of Radiation Oncology, University of Minnesota.

出版信息

Cureus. 2017 Jun 16;9(6):e1360. doi: 10.7759/cureus.1360.

DOI:10.7759/cureus.1360
PMID:28721328
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5510970/
Abstract

Although advances in screening mammography have dramatically improved the early detection of breast cancer, a subset of breast cancer cases still present as locally advanced disease. Some of these patients develop fungating lesions, which are difficult to manage and can have a severe impact on the quality of life. Palliative treatment options include surgery, intra-arterial chemotherapy, and radiation therapy. Herein, we describe the case of a patient who presented with a fungating breast mass and demonstrated an immediate and durable response to radiation therapy with a significantly improved quality of life.

摘要

尽管乳腺钼靶筛查技术的进步显著提高了乳腺癌的早期检测率,但仍有一部分乳腺癌病例以局部晚期疾病的形式出现。其中一些患者会出现溃疡性病变,这些病变难以处理,并且会对生活质量产生严重影响。姑息治疗选择包括手术、动脉内化疗和放射治疗。在此,我们描述了一例出现溃疡性乳腺肿块的患者,该患者对放射治疗表现出即时且持久的反应,生活质量显著改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3398/5510970/87eab90aab51/cureus-0009-00000001360-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3398/5510970/c8a7b7b97efb/cureus-0009-00000001360-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3398/5510970/b088a93f5e93/cureus-0009-00000001360-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3398/5510970/87eab90aab51/cureus-0009-00000001360-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3398/5510970/c8a7b7b97efb/cureus-0009-00000001360-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3398/5510970/b088a93f5e93/cureus-0009-00000001360-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3398/5510970/87eab90aab51/cureus-0009-00000001360-i03.jpg

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Indian J Surg Oncol. 2023 Mar;14(1):93-105. doi: 10.1007/s13193-022-01602-x. Epub 2022 Aug 27.
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Palliative radiation therapy for symptomatic advance breast cancer.姑息性放射治疗对有症状的晚期乳腺癌。

本文引用的文献

1
The Abscopal Effect of Radiation Therapy: What Is It and How Can We Use It in Breast Cancer?放射治疗的远隔效应:是什么以及我们如何在乳腺癌中应用它?
Curr Breast Cancer Rep. 2017;9(1):45-51. doi: 10.1007/s12609-017-0234-y. Epub 2017 Mar 2.
2
Palliation of Ulcerative Breast Lesions with Radiation.溃疡性乳腺病变的放射治疗缓解
Anticancer Res. 2016 Sep;36(9):4701-5. doi: 10.21873/anticanres.11024.
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Endovascular approach to acute hemorrhage in locally advanced breast cancer.局部晚期乳腺癌急性出血的血管内治疗方法。
Sci Rep. 2021 Mar 5;11(1):5282. doi: 10.1038/s41598-021-84872-9.
4
A Patient-Centered Approach for the Treatment of Fungating Breast Wounds.一种以患者为中心的乳腺癌溃疡创面治疗方法。
J Adv Pract Oncol. 2020 Jul;11(5):503-510. doi: 10.6004/jadpro.2020.11.5.6. Epub 2020 Jul 1.
Breast J. 2015 Mar-Apr;21(2):189-91. doi: 10.1111/tbj.12373. Epub 2015 Jan 21.
4
The range and role of palliative interventions for locally advanced breast cancer.局部晚期乳腺癌姑息干预的范围和作用。
Curr Opin Support Palliat Care. 2014 Mar;8(1):70-6. doi: 10.1097/SPC.0000000000000029.
5
Particle embolization to control life-threatening hemorrhage from a fungating locally advanced breast carcinoma: a case report.粒子栓塞术控制晚期局部浸润性乳腺癌的致命性出血:一例报告
J Med Case Rep. 2012 Jul 4;6:186. doi: 10.1186/1752-1947-6-186.
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Immunologic correlates of the abscopal effect in a patient with melanoma.黑色素瘤患者的远隔效应的免疫相关性。
N Engl J Med. 2012 Mar 8;366(10):925-31. doi: 10.1056/NEJMoa1112824.
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Symptoms associated with malignant wounds: a prospective case series.与恶性伤口相关的症状:一项前瞻性病例系列研究。
J Pain Symptom Manage. 2009 Feb;37(2):206-11. doi: 10.1016/j.jpainsymman.2008.01.009. Epub 2008 Jul 10.
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Health-related quality of life in survivors of locally advanced breast cancer: an international randomised controlled phase III trial.局部晚期乳腺癌幸存者的健康相关生活质量:一项国际随机对照III期试验。
Lancet Oncol. 2005 May;6(5):287-94. doi: 10.1016/S1470-2045(05)70100-5.