Yoo Hee-Jeong, Bahn Geonho, Cho In-Hee, Kim Eun-Kyung, Kim Joo-Hyun, Min Jung-Won, Lee Won-Hye, Seo Jun-Seong, Jun Sang-Shin, Bong Guiyoung, Cho Soochurl, Shin Min-Sup, Kim Bung-Nyun, Kim Jae-Won, Park Subin, Laugeson Elizabeth A
Department of Psychiatry, Seoul National University Bundang Hospital, Seongnam, South Korea; Seoul National University College of Medicine, Seoul, South Korea; Seongnam Child and Adolescent Community Mental Health Center, Seongnam, South Korea.
Autism Res. 2014 Feb;7(1):145-61. doi: 10.1002/aur.1354. Epub 2014 Jan 9.
Impaired social functioning is a hallmark feature of autism spectrum disorder (ASD), often requiring treatment throughout the life span. PEERS(®) (Program for the Education and Enrichment of Relational Skills) is a parent-assisted social skills training for teens with ASD. Although PEERS(®) has an established evidence base in improving the social skills of adolescents and young adults with ASD in North America, the efficacy of this treatment has yet to be established in cross-cultural validation trials. The objective of this study is to examine the feasibility and treatment efficacy of a Korean version of PEERS(®) for enhancing social skills through a randomized controlled trial (RCT).The English version of the PEERS(®) Treatment Manual (Laugeson & Frankel, 2010) was translated into Korean and reviewed by 21 child mental health professionals. Items identified as culturally sensitive were surveyed by 447 middle school students, and material was modified accordingly. Participants included 47 teens between 12 and 18 years of age with a diagnosis of ASD and a verbal intelligence quotient (IQ) ≥ 65. Eligible teens were randomly assigned to a treatment group (TG) or delayed treatment control group (CG). Primary outcome measures included questionnaires and direct observations quantifying social ability and problems directly related to ASD. Secondary outcome measures included scales for depressive symptoms, anxiety, and other behavioral problems. Rating scales for parental depressive symptoms and anxiety were examined to detect changes in parental psychosocial functioning throughout the PEERS(®) treatment. Independent samples t-tests revealed no significant differences at baseline across the TG and CG conditions with regard to age (14.04 ± 1.64 and 13.54 ± 1.50 years), IQ (99.39 ± 18.09 & 100.67 ± 16.97), parental education, socioeconomic status, or ASD symptoms (p < 0.05), respectively. Results for treatment outcome suggest that the TG showed significant improvement in communication and social interaction domain scores on the Autism Diagnostic Observation Schedule, interpersonal relationship and play/leisure time on the subdomain scores of the Korean version of the Vineland Adaptive Behavior Scale (p's < 0.01), social skills knowledge total scores on the Test of Adolescent Social Skills Knowledge-Revised (p < 0.01), and decreased depressive symptoms on the Child Depression Inventory following treatment (p < 0.05). Analyses of parental outcome reveal a significant decrease in maternal state anxiety in the TG after controlling for potential confounding variables (p < 0.05). Despite cultural and linguistic differences, the PEERS(®) social skills intervention appears to be efficacious for teens with ASD in Korea with modest cultural adjustment. In an RCT, participants receiving the PEERS(®) treatment showed significant improvement in social skills knowledge, interpersonal skills, and play/leisure skills, as well as a decrease in depressive symptoms and ASD symptoms. This study represents one of only a few cross-cultural validation trials of an established evidence-based treatment for adolescents with ASD.
社交功能受损是自闭症谱系障碍(ASD)的一个标志性特征,通常需要终身治疗。PEERS(®)(关系技能教育与强化项目)是一项由家长辅助的针对患有ASD青少年的社交技能培训。尽管PEERS(®)在改善北美患有ASD的青少年和青年成人的社交技能方面有既定的证据基础,但这种治疗方法在跨文化验证试验中的疗效尚未得到证实。本研究的目的是通过一项随机对照试验(RCT)来检验韩语版PEERS(®)在提高社交技能方面的可行性和治疗效果。将PEERS(®)治疗手册的英文版(劳格森和弗兰克尔,2010年)翻译成韩语,并由21名儿童心理健康专业人员进行审核。447名中学生对被确定为具有文化敏感性的项目进行了调查,并据此对材料进行了修改。参与者包括47名年龄在12至18岁之间、被诊断患有ASD且言语智商(IQ)≥65的青少年。符合条件的青少年被随机分配到治疗组(TG)或延迟治疗对照组(CG)。主要结局指标包括量化社交能力以及与ASD直接相关问题的问卷和直接观察。次要结局指标包括抑郁症状、焦虑和其他行为问题的量表。对父母抑郁症状和焦虑的评定量表进行了检查,以检测在整个PEERS(®)治疗过程中父母心理社会功能的变化。独立样本t检验显示,在基线时,TG组和CG组在年龄(14.04±1.64岁和13.54±1.50岁)、IQ(99.39±18.09和100.67±16.97)、父母教育程度、社会经济地位或ASD症状方面均无显著差异(p<0.05)。治疗结果表明,TG组在自闭症诊断观察量表的沟通和社交互动领域得分、韩语版温兰德适应行为量表子领域得分中的人际关系和游戏/休闲时间方面有显著改善(p<0.01),在青少年社交技能知识修订测试的社交技能知识总分方面有显著改善(p<0.01),并且在治疗后儿童抑郁量表上的抑郁症状有所减轻(p<0.05)。对父母结局的分析显示,在控制潜在混杂变量后,TG组母亲的状态焦虑显著降低(p<0.05)。尽管存在文化和语言差异,但经过适度文化调整后,PEERS(®)社交技能干预对韩国患有ASD的青少年似乎是有效的。在一项RCT中,接受PEERS(®)治疗的参与者在社交技能知识、人际交往技能和游戏/休闲技能方面有显著改善,同时抑郁症状和ASD症状有所减轻。本研究是为数不多的针对患有ASD青少年的既定循证治疗的跨文化验证试验之一。