Olesen Kasper, Rugulies Reiner, Rod Naja Hulvej, Bonde Jens Peter
Department of Occupational and Environmental Medicine, Bispebjerg University Hospital, Copenhagen, Denmark, The National Research Centre for the Working Environment, Copenhagen, Denmark and Social Medicine Section, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Int J Epidemiol. 2014 Feb;43(1):160-7. doi: 10.1093/ije/dyt260. Epub 2014 Jan 9.
Recent studies have suggested that retirement may have beneficial effects on health outcomes. In this study we examined whether the risk of myocardial infarction (MI) was reduced following retirement in a Danish population sample.
Participants were 617 511 Danish workers, born between 1932 and 1948, entering the study at the age of 60, without previous known incidents of ischaemic heart disease. Information on retirement and MI were obtained from Danish national registers. A Cox proportional hazard model was used to address the relation between retirement and onset of MI, while adjusting for age, sex, income, occupational position, education, cohabitation and immigrant status. The participants were followed for up to 7 years.
Of the study population, 3% were diagnosed with MI during follow-up. Retirement was associated with a modestly higher risk of MI with a hazard ratio of 1.11 (95% confidence interval: 1.06, 1.16) when comparing retirees with active workers of the same age.
This study does not support the hypothesis that retirement reduces risk of MI. On the contrary, we find that retirement is associated with a modestly increased risk of MI.
近期研究表明，退休可能对健康状况产生有益影响。在本研究中，我们调查了丹麦人群样本退休后心肌梗死（MI）风险是否降低。
参与者为617511名丹麦工人，出生于1932年至1948年之间，60岁时进入研究，既往无已知缺血性心脏病事件。退休和心肌梗死信息来自丹麦国家登记处。采用Cox比例风险模型分析退休与心肌梗死发病之间的关系，同时对年龄、性别、收入、职业地位、教育程度、同居情况和移民身份进行校正。对参与者进行长达7年的随访。
在研究人群中，3%在随访期间被诊断为心肌梗死。与同龄在职员工相比，退休人员患心肌梗死的风险略高，风险比为1.11（95%置信区间：1.06，1.16）。
本研究不支持退休会降低心肌梗死风险这一假设。相反，我们发现退休与心肌梗死风险适度增加有关。
