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光学频率梳扫频源光学相干断层扫描中连续扫描的两个单片游标调谐激光器的调谐及选择性数据采样

Tuning of successively scanned two monolithic Vernier-tuned lasers and selective data sampling in optical comb swept source optical coherence tomography.

作者信息

Choi Dong-Hak, Yoshimura Reiko, Ohbayashi Kohji

机构信息

Center for Natural Science, Kitasato University, Kitasato 1-15-1, Minamiku, Sagamihara, Kanagawa, 252-0373, Japan.

Graduate School of Medical Sciences, Kitasato University, Kitasato 1-15-1, Minamiku, Sagamihara, Kanagawa, 252-0373, Japan ; Advanced Imaging Co. Ltd., Someino2-23-9, Sakura-shi, Chiba, 285-0831, Japan.

出版信息

Biomed Opt Express. 2013 Nov 22;4(12):2962-87. doi: 10.1364/BOE.4.002962. eCollection 2013.

DOI:10.1364/BOE.4.002962
PMID:24409394
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3862148/
Abstract

Monolithic Vernier tuned super-structure grating distributed Bragg reflector (SSG-DBR) lasers are expected to become one of the most promising sources for swept source optical coherence tomography (SS-OCT) with a long coherence length, reduced sensitivity roll-off, and potential capability for a very fast A-scan rate. However, previous implementations of the lasers suffer from four main problems: 1) frequencies deviate from the targeted values when scanned, 2) large amounts of noise appear associated with abrupt changes in injection currents, 3) optically aliased noise appears due to a long coherence length, and 4) the narrow wavelength coverage of a single chip limits resolution. We have developed a method of dynamical frequency tuning, a method of selective data sampling to eliminate current switching noise, an interferometer to reduce aliased noise, and an excess-noise-free connection of two serially scanned lasers to enhance resolution to solve these problems. An optical frequency comb SS-OCT system was achieved with a sensitivity of 124 dB and a dynamic range of 55-72 dB that depended on the depth at an A-scan rate of 3.1 kHz with a resolution of 15 μm by discretely scanning two SSG-DBR lasers, i.e., L-band (1.560-1.599 μm) and UL-band (1.598-1.640 μm). A few OCT images with excellent image penetration depth were obtained.

摘要

整体式游标调谐超结构光栅分布布拉格反射器(SSG-DBR)激光器有望成为扫频源光学相干断层扫描(SS-OCT)最有前景的光源之一,具有长相干长度、降低的灵敏度滚降以及非常快的A扫描速率的潜在能力。然而,先前的激光器实现存在四个主要问题:1)扫描时频率偏离目标值;2)与注入电流的突然变化相关出现大量噪声;3)由于长相干长度出现光学混叠噪声;4)单个芯片的窄波长覆盖限制了分辨率。我们开发了一种动态频率调谐方法、一种消除电流开关噪声的选择性数据采样方法、一种减少混叠噪声的干涉仪以及两个串联扫描激光器的无过量噪声连接以提高分辨率来解决这些问题。通过离散扫描两个SSG-DBR激光器,即L波段(1.560 - 1.599μm)和UL波段(1.598 - 1.640μm),实现了一种光学频率梳SS-OCT系统,其灵敏度为124dB,动态范围为55 - 72dB,这取决于深度,A扫描速率为3.1kHz,分辨率为15μm。获得了一些具有出色图像穿透深度的OCT图像。

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