Chiabi A, Mah E, Ntsama Essomba M-J, Nguefack S, Mbonda E, Tchokoteu P-F
Service de pédiatrie, hôpital gynéco-obstétrical et pédiatrique de Yaoundé, Yaoundé, Cameroun; Département de pédiatrie, faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun.
Service de pédiatrie, hôpital gynéco-obstétrical et pédiatrique de Yaoundé, Yaoundé, Cameroun; Département de pédiatrie, faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun.
Arch Pediatr. 2014 Feb;21(2):142-6. doi: 10.1016/j.arcped.2013.11.017. Epub 2014 Jan 9.
The rate of survival of very low birth weight neonates (less than 1500 g) is still low in most developing countries, such as Cameroon. The aim of this study was to assess the maternal and neonatal factors that can influence the survival of neonates with birth weights under 1500 g.
This was a retrospective, descriptive, and analytic study of 397 neonates weighing less than 1500 g who were admitted to the Yaounde gynaeco-obstetric and pediatric hospital from May 2003 to December 2011. The chi-squared test and the odds ratio were used to identify risk factors for death. The threshold of significance was P<0.05.
The overall survival rate was 26.5%. The main comorbidities were prematurity (99%), neonatal sepsis (36%), and intrauterine growth retardation (27.2%). The factors that statistically influenced outcome were: parity, birth weight, gestational age, the 5th-min Apgar score, advanced resuscitation at birth, and respiratory distress.
The survival of neonates weighing less than 1500 g depends on several factors, which if acted upon could improve the survival rate.
在大多数发展中国家，如喀麦隆，极低出生体重新生儿（低于1500克）的存活率仍然很低。本研究的目的是评估可能影响出生体重低于1500克新生儿存活的母体和新生儿因素。
这是一项对2003年5月至2011年12月入住雅温得妇产科和儿科医院的397名体重低于1500克新生儿进行的回顾性、描述性和分析性研究。采用卡方检验和比值比来确定死亡的危险因素。显著性阈值为P<0.05。
总体存活率为26.5%。主要合并症为早产（99%）、新生儿败血症（36%）和宫内生长迟缓（27.2%）。在统计学上影响结局的因素有：产次、出生体重、胎龄、5分钟阿氏评分、出生时高级复苏以及呼吸窘迫。
体重低于1500克新生儿的存活取决于多个因素，若对这些因素采取相应措施，可能会提高存活率。
