Schmidt R M, Kuppe G, Kissig B, Ludewig R, Neumann V
Schweiz Arch Neurol Psychiatr (1985). 1987;138(3):13-22.
The diagnostic value of CSF oligoclonal IgG bands, intrathecal IgG synthesis, cytology and markers of myelin breakdown in the cerebro-spinal fluid were evaluated in multiple sclerosis. None of the various immunological alterations were unique to MS. The diagnosis depends therefore mainly on course and clinical symptoms, but can be supported by CSF analysis.
在多发性硬化症中,对脑脊液中寡克隆IgG带、鞘内IgG合成、细胞学及髓鞘破坏标志物的诊断价值进行了评估。各种免疫学改变在多发性硬化症中均非特异性的。因此,诊断主要取决于病程和临床症状,但脑脊液分析可提供支持。