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扁豆(Lens esculenta)种子酶制剂水解二取代海因,用于合成具有线性和环状取代基的α,α-二取代的氨基酸。

Hydrolysis of di-substituted hydantoins, by an enzyme preparation from lentil (Lens esculenta) seeds, for the synthesis of α,α-dialkylated amino acids with linear and cyclic substituents.

机构信息

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出版信息

World J Microbiol Biotechnol. 1996 May;12(3):247-50. doi: 10.1007/BF00360922.

Abstract

Hydrolysis of 5,5'-di-substituted hydantoins with linear and cyclic side chains, to produce the corresponding α,α-dialkylated amino acids and 1-aminocycloalkane-1-carboxylic acids, using an enzyme preparation from lentil (Lens esculenta) seeds is reported for the first time. This method could be developed on a large scale and should be of interest to the chemical and pharmaceutical industries.

摘要

首次报道了利用来自菜豆(Lens esculenta)种子的酶制剂水解 5,5'-二取代海因,生成相应的α,α-二烷基化氨基酸和 1-氨基环烷-1-羧酸。该方法可进行大规模开发,应引起化学和制药工业的兴趣。

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