School of Microbiology and Immunology, The University of New South Wales, NSW, Sydney, 2052, Australia.
World J Microbiol Biotechnol. 1996 Nov;12(6):653-4. doi: 10.1007/BF00327733.
Benzene was metabolized by Rhodococcus sp. 33 through the intradiol cleavage (ortho-) pathway producing cis-benzene glycol, catechol and cis, cis-muconic acid as the intermediates. This is the first elucidation of the pathway by which benzene is degraded by a gram-positive organism. The enzyme assays have also suggested that Rhodococcus 33 does not have a fully functional tricarboxylic acid cycle but may have an operational glyoxylate bypass.
苯被 Rhodococcus sp. 33 通过邻位二醇裂解（ortho-）途径代谢，生成顺式苯二醇、儿茶酚和顺式，顺式粘康酸作为中间体。这是首次阐明了革兰氏阳性菌降解苯的途径。酶分析也表明，Rhodococcus 33 没有完全功能的三羧酸循环，但可能有一个有效的乙醛酸旁路。
