Unit for the Study and Treatment of Pain-ALGOS, Centre de Recerca en Avaluació i Mesura del Comportament, Institut d'Investigació Sanitria Pere Virgili, Universitat Rovira i Virgili, Carretera de Valls s/n, 43007 Tarragona, Catalonia, Spain.
Muscle Nerve. 2014 Jun;49(6):900-5. doi: 10.1002/mus.24079.
We examined the effects of pain site and intensity on function in patients with myotonic dystrophy type 1 (DM1) and facioscapulohumeral muscular dystrophy (FSHD) and chronic pain.
Questionnaires assessing pain sites, pain extent (number of sites), pain intensity, and pain interference were completed by 182 individuals with DM1 (43%) or FSHD (57%) and chronic pain.
There was a positive association between pain extent and intensity with pain interference, and a negative association with psychological functioning in both DM1 and FSHD. Pain intensity at specific sites had differential impact beyond the effects of pain intensity alone. Head pain intensity independently affected psychological functioning, whereas leg, foot, hip, and knee pain contributed independently to the prediction of pain interference.
Pain site and intensity differentially modulates the effect of chronic pain on function in DM1 and FSHD patients. Researchers and clinicians should consider these factors when assessing and treating pain.
我们研究了疼痛部位和强度对 1 型肌强直性营养不良（DM1）和面肩肱型肌营养不良症（FSHD）伴慢性疼痛患者功能的影响。
通过问卷调查评估了 182 名患有 DM1（43%）或 FSHD（57%）和慢性疼痛的个体的疼痛部位、疼痛范围（部位数量）、疼痛强度和疼痛干扰。
在 DM1 和 FSHD 中，疼痛范围和强度与疼痛干扰呈正相关，与心理功能呈负相关。特定部位的疼痛强度除了对疼痛强度的影响外，还具有不同的影响。头部疼痛强度独立影响心理功能，而腿部、脚部、臀部和膝盖疼痛则独立影响疼痛干扰的预测。
疼痛部位和强度会对 DM1 和 FSHD 患者的慢性疼痛对功能的影响产生不同的调节作用。研究人员和临床医生在评估和治疗疼痛时应考虑这些因素。
