Abresch R Ted, Carter Gregory T, Han Jay J, McDonald Craig M
Department of Rehabilitation Medicine, University of California, Davis, 4860 Y Street Suite, 3850, Sacramento, CA 95817, USA.
Phys Med Rehabil Clin N Am. 2012 Aug;23(3):653-73. doi: 10.1016/j.pmr.2012.06.001.
This article reviews the current knowledge regarding the benefits and contraindications of exercise on individuals with neuromuscular diseases (NMDs). Specific exercise prescriptions for individuals with NMDs do not exist because the evidence base is limited. Understanding the effect of exercise on individuals with NMDs requires the implementation of a series of multicenter, randomized controlled trials that are sufficiently powered and use reliable and valid outcome measures to assess the effect of exercise interventions-a major effort for each NMD. In addition to traditional measures of exercise efficacy, outcome variables should include measures of functional status and health-related quality of life.
本文综述了目前关于运动对神经肌肉疾病（NMDs）患者的益处和禁忌的相关知识。由于证据基础有限，目前尚无针对NMDs患者的具体运动处方。要了解运动对NMDs患者的影响，需要开展一系列多中心、随机对照试验，这些试验要有足够的样本量，并使用可靠且有效的结果指标来评估运动干预的效果，而这对于每种NMD来说都是一项艰巨的任务。除了传统的运动效果指标外，结果变量还应包括功能状态和健康相关生活质量的指标。
