Takayuki Yamamoto, Inflammatory Bowel Disease Center and Department of Surgery, Yokkaichi Social Insurance Hospital, Mie 510-0016, Japan.
World J Gastroenterol. 2014 Jan 7;20(1):78-90. doi: 10.3748/wjg.v20.i1.78.
Many patients with Crohn's disease (CD) require surgery. Indications for surgery include failure of medical treatment, bowel obstruction, fistula or abscess formation. The most common surgical procedure is resection. In jejunoileal CD, strictureplasty is an accepted surgical technique that relieves the obstructive symptoms, while preserving intestinal length and avoiding the development of short bowel syndrome. However, the role of strictureplasty in duodenal and colonic diseases remains controversial. In extensive colitis, after total colectomy with ileorectal anastomosis (IRA), the recurrence rates and functional outcomes are reasonable. For patients with extensive colitis and rectal involvement, total colectomy and end-ileostomy is safe and effective; however, a few patients can have subsequent IRA, and half of the patients will require proctectomy later. Proctocolectomy is associated with a high incidence of delayed perineal wound healing, but it carries a low recurrence rate. Patients undergoing proctocolectomy with ileal pouch-anal anastomosis had poor functional outcomes and high failure rates. Laparoscopic surgery has been introduced as a minimal invasive procedure. Patients who undergo laparoscopic surgery have a more rapid recovery of bowel function and a shorter hospital stay. The morbidity also is lower, and the rate of disease recurrence is similar compared with open procedures.
许多克罗恩病(CD)患者需要手术。手术指征包括药物治疗失败、肠梗阻、瘘管或脓肿形成。最常见的手术方法是切除术。在回肠空肠 CD 中,狭窄成形术是一种公认的手术技术,它可以缓解梗阻症状,同时保留肠长度并避免短肠综合征的发生。然而,狭窄成形术在十二指肠和结肠疾病中的作用仍存在争议。在广泛性结肠炎中,全结肠切除加回肠直肠吻合术(IRA)后,复发率和功能结局是合理的。对于广泛性结肠炎和直肠受累的患者,全结肠切除和末端回肠造口术是安全有效的;然而,少数患者可能随后进行 IRA,一半的患者以后需要行直肠切除术。直肠结肠切除术与较高的会阴伤口愈合延迟发生率相关,但复发率较低。接受回肠袋肛管吻合术的直肠结肠切除术患者的功能结局较差,失败率较高。腹腔镜手术已被引入作为一种微创程序。接受腹腔镜手术的患者肠道功能恢复更快,住院时间更短。发病率也较低,与开放手术相比,疾病复发率相似。