环境氨对鱼类肌肉和鳃中AMP脱氨酶催化潜力的影响。

Ambient ammonia effect on catalytic potential of muscle and gill AMP deaminase in fish.

作者信息

Sashikala R, Mohan P K, Indira K

出版信息

Arch Int Physiol Biochim. 1987 Mar;95(1):31-5. doi: 10.3109/13813458709075022.

Abstract

AMP deaminase activity was inhibited in gill and muscle of Sarotherodon mossambicus, subjected to a week-long exposure to sublethal concentration of ambient ammonia. pH-dependent kinetic studies revealed decreased catalytic efficiency of the enzyme due to altered active site density and ionization pattern in the fish tissues at different phases of ammonia exposure.

摘要

莫桑比克罗非鱼的鳃和肌肉中的AMP脱氨酶活性受到抑制，该鱼暴露于亚致死浓度的环境氨中长达一周。pH依赖性动力学研究表明，由于在氨暴露的不同阶段鱼组织中活性位点密度和电离模式的改变，该酶的催化效率降低。