慢性淋巴细胞白血病的“自发”完全缓解：三例报告及文献复习
"Spontaneous" complete remissions in chronic lymphocytic leukemia: report of three cases and review of the literature.
作者信息
Ribera J M, Viñolas N, Urbano-Ispizua A, Gallart T, Montserrat E, Rozman C
出版信息
Blood Cells. 1987;12(2):471-83.
"Spontaneous" complete remissions (SCR) are a rare event in chronic lymphocytic leukemia (CLL). In this article, we report three cases of SCR observed in a series of 285 patients followed at a single institution during the last 15 years. SCR was documented by clinical and hematologic data, including bone marrow biopsy, and immune cell markers. A delay of 0.9-1.6 years between "clinical" and "clonal" remission was observed. A review of other cases of SCR in CLL is also performed.
“自发”完全缓解（SCR）在慢性淋巴细胞白血病（CLL）中是罕见事件。在本文中，我们报告了在过去15年于单一机构随访的285例患者中观察到的3例SCR病例。SCR通过临床和血液学数据得以记录，包括骨髓活检以及免疫细胞标志物。观察到“临床”缓解与“克隆性”缓解之间存在0.9 - 1.6年的延迟。我们还对CLL中其他SCR病例进行了综述。
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