Organisch-Chemisches Institut der Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 270, D-69120 Heidelberg, Germany.
J Am Chem Soc. 2014 Jan 29;136(4):1272-5. doi: 10.1021/ja411869r. Epub 2014 Jan 21.
A highly enantioselective and regioselective Ir-catalyzed allylic esterification is described, in which branched allylic esters are synthesized directly. Carboxylates were used as nucleophiles and linear allylic phosphates as electrophiles. In some cases the allylic substitution reaction was found to be accompanied by a kinetic resolution process, which causes a change of the enantiomeric excess.
描述了一种高对映选择性和区域选择性的 Ir 催化烯丙基酯化反应，其中直接合成支链烯丙基酯。羧酸酯作为亲核试剂，线性烯丙基磷酸酯作为亲电试剂。在某些情况下，发现烯丙基取代反应伴随着动力学拆分过程，这导致对映体过量的变化。
