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基于蒙特卡罗的放射色胶片在高能近距离放射治疗剂量学中吸收剂量能量依赖性的研究。

Monte Carlo-based investigation of absorbed-dose energy dependence of radiochromic films in high energy brachytherapy dosimetry.

机构信息

Bhabha Atomic Research Centre.

出版信息

J Appl Clin Med Phys. 2014 Jan 6;15(1):4448. doi: 10.1120/jacmp.v15i1.4448.

Abstract

Relative absorbed dose energy response correction, R, for various radiochromic films in water phantom is calculated by the use of the Monte Carlo-based EGSnrc code system for high energy brachytherapy sources 60Co, 137Cs, 192Ir and 169Yb. The corrections are calculated along the transverse axis of the sources (1-15 cm). The radiochromic films investigated are EBT, EBT2 (lot 020609 and lot 031109), RTQA, XRT, XRQA, and HS. For the 60Co source, the value of R is about unity and is independent of distance in the water phantom for films other than XRT and XRQA. The XRT and XRQA films showed distance dependent R values for this source (the values of R at 15 cm from the source in water are 1.845 and 2.495 for the films XRT and XRQA, respectively). In the case of 137Cs and 192Ir sources, XRT, XRQA, EBT2 (lot 031109), and HS films showed distant-dependent R values. The rest of the films showed no energy dependence (HS film showed R values less than unity by about 5%, whereas the other films showed R values higher than unity). In the case of 169Yb source, the EBT film showed no energy dependence and EBT2 film (lot 031109) showed a distance-independent R value of 1.041. The rest of the films showed distance-dependent R values (increases with distance for the films other than HS). The solid phantoms PMMA and polystyrene enhance the R values for some films when compared the same in the water phantom.

摘要

使用基于蒙特卡罗的 EGSnrc 代码系统,针对高能近距离放射治疗源 60Co、137Cs、192Ir 和 169Yb,计算了水模体中各种光致变色胶片的相对吸收剂量能量响应校正值 R。校正值沿源的横向轴(1-15cm)计算。研究的光致变色胶片有 EBT、EBT2(Lot020609 和 Lot031109)、RTQA、XRT、XRQA 和 HS。对于 60Co 源,除了 XRT 和 XRQA 之外,其它胶片的 R 值约为 1,且在水模体中与距离无关。对于该源,XRT 和 XRQA 胶片的 R 值随距离而变化(胶片在水模体中距离源 15cm 处的 R 值分别为 1.845 和 2.495)。对于 137Cs 和 192Ir 源,XRT、XRQA、EBT2(Lot031109)和 HS 胶片显示出随距离变化的 R 值。其余胶片没有能量依赖性(HS 胶片的 R 值约低 5%,而其它胶片的 R 值则高于 1)。对于 169Yb 源,EBT 胶片没有能量依赖性,EBT2 胶片(Lot031109)显示出与距离无关的 R 值为 1.041。其余胶片显示出随距离变化的 R 值(除了 HS 之外,胶片的 R 值随距离增加而增加)。与在水模体中相比,PMMA 和聚苯乙烯固体模体增强了一些胶片的 R 值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb50/5711229/871478d0616c/ACM2-15-351-g001.jpg

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