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识别门诊宫腔镜检查时不可接受疼痛的预测因素。

Identifying predictors of unacceptable pain at office hysteroscopy.

作者信息

de Freitas Fonseca Márlon, Sessa Felipe V, Resende José Anacleto D, Guerra Camilla Gabriely S, Andrade Claudio M, Crispi Claudio P

机构信息

Departments of Anesthesiology and Gynecology, Instituto Fernandes Figueira, Rio de Janeiro, Brazil.

Departments of Anesthesiology and Gynecology, Instituto Fernandes Figueira, Rio de Janeiro, Brazil.

出版信息

J Minim Invasive Gynecol. 2014 Jul-Aug;21(4):586-91. doi: 10.1016/j.jmig.2013.12.118. Epub 2014 Jan 11.

DOI:10.1016/j.jmig.2013.12.118
PMID:24423975
Abstract

STUDY OBJECTIVE

To identify predictors of unacceptable pain during office hysteroscopy without anesthesia.

DESIGN

Prospective observational study (Canadian Task Force classification II-2).

SETTING

Teaching hospital.

PATIENTS

Five hundred fifty-eight women aged 17 to 73 years.

INTERVENTION

Elective office hysteroscopy without anesthesia.

MEASUREMENTS AND MAIN RESULTS

Pain intensity was assessed via a verbal rating scale (VRS, 0-10). Pain was considered unacceptable when severe during the procedure (VRS ≥7) or moderate to severe at discharge (VRS ≥4). After preliminary statistical analysis, factors including diabetes, age ≤50 years, previous curettage, dyspareunia, severe dysmenorrhea, and hysteroscopist experience were selected to compose 2 binary multivariate models to predict unacceptable pain. As expected, hysteroscopist experience was protective against unacceptable pain during office hysteroscopy (p = .03; adjusted odds ratio [OR], 0.63; 95% confidence interval [CI], 41-96) and also at discharge (p = .002; adjusted OR, 0.48; 95% CI, 30-77). Severe dysmenorrhea was a significant risk factor for pain (cramps) at discharge (p < .001; adjusted OR, 3.07; 95% CI, 1.97-4.78).

CONCLUSION

Women with severe dysmenorrhea will benefit from preemptive analgesia regardless of hysteroscopist level of experience because this condition significantly increased the occurrence of unacceptable cramps at discharge.

摘要

研究目的

确定在未麻醉的门诊宫腔镜检查期间出现难以忍受疼痛的预测因素。

设计

前瞻性观察性研究(加拿大工作组分类II - 2)。

地点

教学医院。

患者

558名年龄在17至73岁之间的女性。

干预措施

未麻醉的择期门诊宫腔镜检查。

测量指标及主要结果

通过言语评定量表(VRS,0 - 10)评估疼痛强度。当术中疼痛严重(VRS≥7)或出院时中度至重度(VRS≥4)时,疼痛被认为难以忍受。经过初步统计分析,选择糖尿病、年龄≤50岁、既往刮宫史、性交困难、严重痛经和宫腔镜检查医生经验等因素组成两个二元多变量模型,以预测难以忍受的疼痛。正如预期的那样,宫腔镜检查医生的经验可预防门诊宫腔镜检查期间难以忍受的疼痛(p = 0.03;调整后的优势比[OR],0.63;95%置信区间[CI],41 - 96),在出院时也是如此(p = 0.002;调整后的OR,0.48;95%CI,30 - 77)。严重痛经是出院时疼痛(痉挛)的一个重要危险因素(p < 0.001;调整后的OR,3.07;95%CI,1.97 - 4.78)。

结论

患有严重痛经的女性无论宫腔镜检查医生的经验水平如何,都将从预防性镇痛中获益,因为这种情况会显著增加出院时难以忍受的痉挛的发生率。

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