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得舒饮食对妊娠期糖尿病患者妊娠结局的影响:一项随机对照临床试验

The effect of DASH diet on pregnancy outcomes in gestational diabetes: a randomized controlled clinical trial.

作者信息

Asemi Z, Samimi M, Tabassi Z, Esmaillzadeh A

机构信息

Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran.

Department of Gynecology and Obstetrics, School of Medicine, Kashan University of Medical Sciences, Kashan, Iran.

出版信息

Eur J Clin Nutr. 2014 Apr;68(4):490-5. doi: 10.1038/ejcn.2013.296. Epub 2014 Jan 15.

Abstract

BACKGROUND/OBJECTIVES: The current study was performed to investigate the effects of the Dietary Approaches to Stop Hypertension (DASH) eating plan on pregnancy outcomes in pregnant women with gestational diabetes mellitus (GDM).

SUBJECTS/METHODS: This randomized controlled clinical trial was performed among 52 women diagnosed with GDM. Participants were randomly assigned to consume either the control (n=26) or the DASH diet (n=26) for 4 weeks. The control diet was designed to contain 45-55% carbohydrates, 15-20% protein and 25-30% total fat. The DASH diet was rich in fruits, vegetables, whole grains and low-fat dairy products, and contained lower amounts of saturated fats, cholesterol and refined grains with a total of 2400 mg/day sodium. The numbers of women who commenced insulin therapy after dietary intervention, the mode of delivery and prevalence of polyhydramnios were assessed. The length, weight and head circumference of infants were measured during the first 24 h after birth.

RESULTS

Whereas 46.2% of women in the DASH diet needed to have a cesarean section, this percentage for the control group was 80.8% (P=0.01). The percentage of those who needed to commence insulin therapy after intervention was also significantly different between the two groups (23% for DASH vs 73% for control group, P<0.0001). Infants born to mothers on the DASH diet had significantly lower weight (3222.7 vs 3818.8 g, P<0.0001), head circumference (34.2 vs 35.1 cm, P=0.01) and ponderal index (2.50 vs 2.87 kg/m(3), P<0.0001) compared with those born to mothers on the control diet.

CONCLUSIONS

In conclusion, consumption of DASH diet for 4 weeks among pregnant women with GDM resulted in improved pregnancy outcomes.

摘要

背景/目的:本研究旨在探讨终止高血压膳食疗法(DASH)饮食计划对妊娠期糖尿病(GDM)孕妇妊娠结局的影响。

对象/方法:本随机对照临床试验在52例诊断为GDM的女性中进行。参与者被随机分配食用对照饮食(n = 26)或DASH饮食(n = 26),为期4周。对照饮食设计为含有45 - 55%的碳水化合物、15 - 20%的蛋白质和25 - 30%的总脂肪。DASH饮食富含水果、蔬菜、全谷物和低脂乳制品,饱和脂肪、胆固醇和精制谷物含量较低,钠含量共2400毫克/天。评估饮食干预后开始胰岛素治疗的女性人数、分娩方式和羊水过多的患病率。在出生后的头24小时内测量婴儿的身长、体重和头围。

结果

DASH饮食组46.2%的女性需要剖宫产,而对照组这一比例为80.8%(P = 0.01)。两组干预后需要开始胰岛素治疗的比例也有显著差异(DASH组为23%,对照组为73%,P < 0.0001)。与对照饮食组母亲所生婴儿相比,DASH饮食组母亲所生婴儿的体重(3222.7对3818.8克,P < 0.0001)、头围(34.2对35.1厘米,P = 0.01)和 ponderal指数(2.50对2.87千克/立方米,P < 0.0001)显著更低。

结论

总之,GDM孕妇食用4周DASH饮食可改善妊娠结局。

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