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甘丙肽和神经肽Y样免疫反应共存于猫的椎旁交感神经元中。

Galanin- and neuropeptide Y-like immunoreactivities coexist in paravertebral sympathetic neurones of the cat.

作者信息

Kummer W

出版信息

Neurosci Lett. 1987 Jul 22;78(2):127-31. doi: 10.1016/0304-3940(87)90620-3.

Abstract

Paraffin sections of feline cervicothoracic sympathetic ganglia were investigated for galanin-like immunoreactivity (galanin-LI) by means of immunohistochemistry. Galanin-LI was observed in postganglionic neurones, which, as revealed by investigation of adjacent sections, also displayed neuropeptide Y (NPY)-LI. Additional NPY-LI ganglion cells were devoid of galanin-LI. Galanin-LI did not coexist with vasoactive intestinal polypeptide-LI in neurones. Galanin-LI nerve fibres and paraganglionic cells were few in number. The findings suggest that galanin may participate in sympathetic control of organ function.

摘要

采用免疫组织化学方法,对猫颈胸交感神经节的石蜡切片进行了甘丙肽样免疫反应性(galanin-LI)研究。在节后神经元中观察到了甘丙肽样免疫反应性,通过对相邻切片的研究发现,这些神经元也显示出神经肽Y(NPY)样免疫反应性。另外一些NPY样免疫反应性神经节细胞则没有甘丙肽样免疫反应性。甘丙肽样免疫反应性在神经元中不与血管活性肠肽样免疫反应性共存。甘丙肽样免疫反应性神经纤维和副神经节细胞数量较少。这些发现提示甘丙肽可能参与对器官功能的交感神经控制。

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