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头颈部区域的上皮-肌上皮癌

Epithelial myoepithelial carcinoma of head and neck region.

作者信息

Arora Sowrabh Kumar, Sharma Nishi, Bhardwaj Minakshi

机构信息

Department of Otolaryngology, Dr. Ram Manohar Lohia Hospital, Baba Khadag Singh Marg, 110001 New Delhi, India.

Department of Pathology, Dr. Ram Manohar Lohia Hospital, New Delhi, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2013 Jul;65(Suppl 1):163-6. doi: 10.1007/s12070-011-0414-4. Epub 2012 Jan 20.

Abstract

The objective of the study is to document the clinical, histopathological and immunological findings of epithelial myoepithelial carcinoma (EMEC) which is an uncommon neoplasm. The tumour represents less than 0.5-1% of all salivary gland neoplasms. As per literature, it involves the parotid gland most frequently and rarely, the minor salivary glands. We are reporting a series of four cases of EMEC over a period of one and half years, three from minor salivary glands at different sites and one from the deep lobe of parotid. Interestingly, the pre operative FNAC of all the cases revealed benign pathology. Recurrence occurred in three of them after tumour excision. One patient was subjected to post operative radiotherapy and one patient to chemotherapy. Histopathology and immunohistochemistry is very important in this tumour. There is no definitive guideline of treatment in post operative recurrence cases.

摘要

本研究的目的是记录上皮-肌上皮癌(EMEC)的临床、组织病理学和免疫学表现,这是一种罕见的肿瘤。该肿瘤占所有涎腺肿瘤的比例不到0.5%-1%。根据文献,它最常累及腮腺,很少累及小涎腺。我们报告了在一年半的时间里的4例EMEC病例,其中3例来自不同部位的小涎腺,1例来自腮腺深叶。有趣的是,所有病例的术前细针穿刺抽吸活检(FNAC)均显示为良性病理结果。其中3例在肿瘤切除后复发。1例患者接受了术后放疗,1例患者接受了化疗。组织病理学和免疫组织化学在该肿瘤中非常重要。术后复发病例尚无明确的治疗指南。

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