Shraddha Jain, Priya Madhu, Sunil Kumar
Department of Otolaryngology and HNS, JNMC, Sawangi (Meghe), Wardha, Maharashtra India.
Department of Otolaryngology and HNS, IGIMS, Patna, India.
Indian J Otolaryngol Head Neck Surg. 2013 Jul;65(Suppl 1):178-81. doi: 10.1007/s12070-011-0428-y. Epub 2012 Jan 6.
We report a case of melanocarcinoma of sino-nasal region in a 42 year old female who presented with brownish-colored sino-nasal mass involving left orbit, spontaneous epistaxis, facial swelling on left side, and ulceration of overlying skin, cervical and distant metastasis in liver over a short time span of 3 months. On biopsy, the mass was diagnosed as melanocarcinoma of nose and paranasal sinuses. Primary mucosal malignant melanoma of the nasal cavity, paranasal sinuses, and nasopharynx is an aggressive disease and fortunately rare with current research data being mainly from western populations. The disease is known to be more common among elderly population in their seventies and to follow a prolonged course due to innocuous symptoms. This case is being reported for its rarity in our geographical region, early age of presentation and rapid progression of the disease over a span of 3 months.
我们报告一例42岁女性鼻窦黑色素瘤病例，该患者出现累及左侧眼眶的褐色鼻窦肿物、自发性鼻出血、左侧面部肿胀、覆盖皮肤溃疡，且在短短3个月内出现颈部及远处肝脏转移。活检显示，肿物被诊断为鼻及鼻窦黑色素瘤。鼻腔、鼻窦和鼻咽部原发性黏膜恶性黑色素瘤是一种侵袭性疾病，幸运的是较为罕见，目前的研究数据主要来自西方人群。已知该疾病在70多岁的老年人群中更为常见，且由于症状不明显而病程较长。报告该病例是因其在我们所在地理区域的罕见性、发病年龄较早以及疾病在3个月内的快速进展。
