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单侧鼻腔肿物的临床病理及影像学特征综述。

A review of the clinicopathological and radiological features of unilateral nasal mass.

作者信息

Nair Satish, James E, Awasthi S, Nambiar Sapna, Goyal Sunil

机构信息

Army Hospital Research and Referral, New Delhi, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2013 Aug;65(Suppl 2):199-204. doi: 10.1007/s12070-011-0288-5. Epub 2011 Aug 27.

Abstract

Unilateral sinonasal pathology are common presentations but are regarded with caution as neoplastic conditions during their early stages may mimic an inflammatory pathology. The aim of the review was to analyse the varied presentations of patients with unilateral nasal mass and to identify features suggestive of neoplastic pathology. A retrospective review of all cases of unilateral nasal mass/polyp from Jan 09 to Jan 10 presenting at a tertiary care hospital were analysed. The patients were grouped as per their histopathological diagnosis as inflammatory and neoplastic. The demographic data, presenting symptoms, radiological and histopathological findings were compared between the two groups. Out of the 53 patients of unilateral nasal mass, 44 (83.1%) had inflammatory conditions and 9 (16.9%) had neoplastic conditions. Benign nasal polyp and inverted papilloma were the commonest inflammatory and neoplastic condition. Neoplastic conditions were significantly commoner in males (P = 0.0315) and in the age group above 50 years (P = 0.0046). Epistaxis and extranasal symptoms like facial pain, dental and orbital complaints were found to be significantly higher in neoplastic conditions. Neoplastic lesions of nose and paranasal sinus are one of the most challenging conditions that otolaryngologists have to diagnose and treat due to their hidden nature and late presentations. In our review neoplastic conditions were found to be higher in elderly male with epistaxis, extranasal symptoms and presence of extensive soft tissue involvement and bony destruction on CT scan. The clinician should have a high index of suspicion to rule out a neoplastic aetiology in all cases of unilateral nasal mass.

摘要

单侧鼻窦病变很常见,但在早期阶段可能会被谨慎对待,因为肿瘤性疾病可能会模仿炎症性病变。本综述的目的是分析单侧鼻腔肿物患者的各种表现,并确定提示肿瘤性病变的特征。对2009年1月至2010年1月在一家三级医院就诊的所有单侧鼻腔肿物/息肉病例进行了回顾性分析。根据组织病理学诊断将患者分为炎症性和肿瘤性两组。比较两组患者的人口统计学数据、临床表现、影像学和组织病理学检查结果。在53例单侧鼻腔肿物患者中,44例(83.1%)为炎症性疾病,9例(16.9%)为肿瘤性疾病。鼻息肉和内翻性乳头状瘤分别是最常见的炎症性和肿瘤性疾病。肿瘤性疾病在男性(P = 0.0315)和50岁以上年龄组(P = 0.0046)中明显更为常见。鼻出血以及鼻外症状如面部疼痛、牙齿和眼眶不适在肿瘤性疾病中显著更高。鼻和鼻窦的肿瘤性病变是耳鼻喉科医生必须诊断和治疗的最具挑战性的疾病之一,因为它们具有隐匿性和出现较晚的特点。在我们的综述中,发现老年男性中肿瘤性疾病较多,伴有鼻出血、鼻外症状以及CT扫描显示广泛的软组织受累和骨质破坏。临床医生在所有单侧鼻腔肿物病例中都应保持高度怀疑,以排除肿瘤性病因。

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本文引用的文献

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Unilateral nasal polyposis: clinical presentation and pathology.单侧鼻息肉病:临床表现与病理
Am J Otolaryngol. 2008 Jul-Aug;29(4):230-2. doi: 10.1016/j.amjoto.2007.07.001. Epub 2008 Mar 17.
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Sinonasal verrucous carcinoma with oral invasion.伴有口腔侵犯的鼻窦疣状癌。
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