甜叶菊中一种六-β-D-吡喃葡萄糖基二萜的分离、表征及感官评价

Isolation, characterization and sensory evaluation of a Hexa beta-D-glucopyranosyl diterpene from Stevia rebaudiana.

作者信息

Prakash Indra, Chaturvedula Venkata Sai Prakash, Markosyan Avetik

机构信息

The Coca-Cola Company, Organic Chemistry Department, Global Research and Development, One Coca-Cola Plaza, Atlanta, GA 30313, USA.

PureCircle SDN BHD, Lengkuk Teknologi, 71760 Bandar ENSTEK, Negeri Sembilan, Malaysia.

出版信息

Nat Prod Commun. 2013 Nov;8(11):1523-6.

PMID:24427932

Abstract

From the extract of the leaves of Stevia rebaudiana Bertoni, a diterpene glycoside was isolated which was identified as 13-[(2-O-beta-D-glucopyranosyl-3-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy] ent-kaur-16-en-19-oic acid-(2-O-beta-D-glucopyranosyl-3-O-beta-D-glucopyranosyl-D-glucopyranosyl) ester (1). The complete 1H and 13C NMR assignment of 1 is reported for the first time, from extensive NMR (1H and 13C, COSY, HSQC, and HMBC) and mass spectral data. Also, we report the sensory evaluation of 1 against sucrose for the sweetness property of this molecule.

摘要

从甜叶菊的叶子提取物中分离出一种二萜糖苷，其被鉴定为13 - [(2 - O - β - D - 吡喃葡萄糖基 - 3 - O - β - D - 吡喃葡萄糖基 - β - D - 吡喃葡萄糖基)氧基] 对映 - 贝壳杉 - 16 - 烯 - 19 - 酸 - (2 - O - β - D - 吡喃葡萄糖基 - 3 - O - β - D - 吡喃葡萄糖基 - D - 吡喃葡萄糖基)酯（1）。首次根据广泛的核磁共振（1H和13C、COSY、HSQC和HMBC）及质谱数据报道了1的完整1H和13C核磁共振归属。此外，我们还报道了1相对于蔗糖的感官评价，以评估该分子的甜味特性。