van der Aa N E, Benders M J N L, Groenendaal F, de Vries L S
Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.
Acta Paediatr. 2014 Apr;103(4):356-64. doi: 10.1111/apa.12555. Epub 2014 Feb 11.
Neonatal stroke, including perinatal arterial ischaemic stroke and cerebral sinovenous thrombosis, remains a serious problem in the neonate. This article reviews the current evidence on epidemiology, pathogenesis, diagnostics and therapeutic options.
Although our understanding of the underlying mechanisms and possible risk factors has improved, little progress has been made towards therapeutic options. Considering the high incidence of neurological sequelae, the need for therapeutic options is high and should be the focus of future research.
新生儿卒中，包括围产期动脉缺血性卒中和脑静脉窦血栓形成，仍然是新生儿期的一个严重问题。本文综述了关于流行病学、发病机制、诊断和治疗选择的当前证据。
尽管我们对潜在机制和可能的危险因素的理解有所提高，但在治疗选择方面进展甚微。鉴于神经后遗症的高发生率，对治疗选择的需求很高，应成为未来研究的重点。
