凯尔氏病

Kyrle's disease.

作者信息

Ataseven Arzu, Ozturk Perihan, Kucukosmanoglu Iknur, Kurtipek Gulcan Saylam

机构信息

Konya Training and Research Hospital, Konya, Turkey.

出版信息

BMJ Case Rep. 2014 Jan 15;2014:bcr2013009905. doi: 10.1136/bcr-2013-009905.

DOI:10.1136/bcr-2013-009905

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3903330/

Abstract

Kyrle's disease (KD) is a dermatosis which was first described by Kyrle as "hyperkeratosis follicularis et parafollicularis in cutem penetrans" in 1916. Perforating dermatoses are a heterogeneous disorder group characterised by transepithelial elimination. KD has been seen in association with multiple disorders, including diabetes mellitus, renal and liver diseases, congestive heart failure, hyperlipidaemia, infective diseases and abnormal metabolism of vitamin A. This case report presents two patients with KD with associated systemic disease.

摘要

凯尔氏病（KD）是一种皮肤病，1916年凯尔首次将其描述为“穿通性毛囊和毛囊周角化过度”。穿通性皮肤病是一组异质性疾病，其特征为经上皮排除。KD已被发现与多种疾病相关，包括糖尿病、肾和肝脏疾病、充血性心力衰竭、高脂血症、感染性疾病以及维生素A代谢异常。本病例报告介绍了两名患有KD并伴有全身性疾病的患者。

相似文献

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Kyrle's disease.

BMJ Case Rep. 2014 Jan 15;2014:bcr2013009905. doi: 10.1136/bcr-2013-009905.

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Hyperkeratosis Follicularis et Parafollicularis in Cutem Penetrans (Kyrle).

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[On the differential diagnosis of hyperkeratosis follicularis and parafollicularis in cutem penetrans (Kyrle's disease) from elastosis perfans serpiginosa (Lutz-Miescher disease)].

Hautarzt. 1968 Jun;19(6):259-64.

引用本文的文献

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Kyrle disease: a systematic review of clinical features, diagnostic approaches, dermatoscopic insights, systemic associations, and therapeutic strategies.

Arch Dermatol Res. 2025 Mar 23;317(1):622. doi: 10.1007/s00403-025-04067-4.

2

Acquired reactive perforating collagenosis triggered by trauma with eosinophilia: a case report and literature review.

Front Med (Lausanne). 2024 Jun 26;11:1415545. doi: 10.3389/fmed.2024.1415545. eCollection 2024.

3

Generalized Lesions of Kyrle's Disease: A Rare Case.

Int Med Case Rep J. 2022 Apr 12;15:187-191. doi: 10.2147/IMCRJ.S358523. eCollection 2022.

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