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凯尔氏病

Kyrle's disease.

作者信息

Ataseven Arzu, Ozturk Perihan, Kucukosmanoglu Iknur, Kurtipek Gulcan Saylam

机构信息

Konya Training and Research Hospital, Konya, Turkey.

出版信息

BMJ Case Rep. 2014 Jan 15;2014:bcr2013009905. doi: 10.1136/bcr-2013-009905.

DOI:10.1136/bcr-2013-009905
PMID:24429045
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3903330/
Abstract

Kyrle's disease (KD) is a dermatosis which was first described by Kyrle as "hyperkeratosis follicularis et parafollicularis in cutem penetrans" in 1916. Perforating dermatoses are a heterogeneous disorder group characterised by transepithelial elimination. KD has been seen in association with multiple disorders, including diabetes mellitus, renal and liver diseases, congestive heart failure, hyperlipidaemia, infective diseases and abnormal metabolism of vitamin A. This case report presents two patients with KD with associated systemic disease.

摘要

凯尔氏病（KD）是一种皮肤病，1916年凯尔首次将其描述为“穿通性毛囊和毛囊周角化过度”。穿通性皮肤病是一组异质性疾病，其特征为经上皮排除。KD已被发现与多种疾病相关，包括糖尿病、肾和肝脏疾病、充血性心力衰竭、高脂血症、感染性疾病以及维生素A代谢异常。本病例报告介绍了两名患有KD并伴有全身性疾病的患者。

相似文献

1
Kyrle's disease.凯尔氏病
BMJ Case Rep. 2014 Jan 15;2014:bcr2013009905. doi: 10.1136/bcr-2013-009905.
2
Hyperkeratosis Follicularis et Parafollicularis in Cutem Penetrans (Kyrle).穿通性毛囊和毛囊旁角化病（凯尔里病）
Proc R Soc Med. 1947 Mar;40(5):262. doi: 10.1177/003591574704000528.
3
[KYRLE'S "HYPERKERATOSIS FOLLICULARIS ET PARAFOLLICULARIS IN CUTEM PENETRANS"].[凯尔氏“毛囊及毛囊旁角质栓性穿通性过度角化症”]
Minerva Dermatol. 1963 Oct;38:318-23.
4
[Hyperkeratosis follicularis et parafollicularis in cutem penetrans (Kyrle's disease)].[穿通性毛囊和毛囊旁角化过度症（凯尔里病）]
G Ital Dermatol. 1955 Mar-Apr;96(2):125-41.
5
[Kyrle's disease. Synonym: hyperkeratosis follicularis et parafollicularis in cutem penetrans. Report of a case].[凯尔氏病。同义词：穿通性皮肤毛囊和毛囊旁角化过度症。病例报告]
Med Cutan Ibero Lat Am. 1986;14(2):143-5.
6
[Kyrle's disease].[凯尔氏病]
Med Pregl. 2002 Jan-Feb;55(1-2):47-50. doi: 10.2298/mpns0202047g.
7
Kyrle's disease.凯尔氏病
Cutis. 1979 Apr;23(4):463-6.
8
Hyperkeratosis follicularis et parafollicularis in cutem penetrans (?Kyrle's disease).
Br J Dermatol. 1970 Sep;83(3):420-2.
9
Kyrle's disease. Hyperkeratosis follicularis et parafollicularis in cutem penetrans.
Acta Derm Venereol. 1973;53(6):505-8.
10
[On the differential diagnosis of hyperkeratosis follicularis and parafollicularis in cutem penetrans (Kyrle's disease) from elastosis perfans serpiginosa (Lutz-Miescher disease)].
Hautarzt. 1968 Jun;19(6):259-64.

引用本文的文献

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Kyrle disease: a systematic review of clinical features, diagnostic approaches, dermatoscopic insights, systemic associations, and therapeutic strategies.Kyrle病：临床特征、诊断方法、皮肤镜观察、全身关联及治疗策略的系统评价
Arch Dermatol Res. 2025 Mar 23;317(1):622. doi: 10.1007/s00403-025-04067-4.
2
Acquired reactive perforating collagenosis triggered by trauma with eosinophilia: a case report and literature review.创伤伴嗜酸性粒细胞增多引发的获得性反应性穿通性胶原病：一例报告及文献复习
Front Med (Lausanne). 2024 Jun 26;11:1415545. doi: 10.3389/fmed.2024.1415545. eCollection 2024.
3
Generalized Lesions of Kyrle's Disease: A Rare Case.凯尔氏病的全身性病变：一例罕见病例。
Int Med Case Rep J. 2022 Apr 12;15:187-191. doi: 10.2147/IMCRJ.S358523. eCollection 2022.

本文引用的文献

1
Acquired reactive perforating collagenosis.获得性反应性穿通性胶原病
Eurasian J Med. 2012 Apr;44(1):51-3. doi: 10.5152/eajm.2012.11.
2
Cutaneous manifestations in patients with chronic kidney disease on maintenance hemodialysis.维持性血液透析慢性肾脏病患者的皮肤表现
ISRN Dermatol. 2012;2012:679619. doi: 10.5402/2012/679619. Epub 2012 Jul 5.
3
A prospective study of cutaneous abnormalities in patients with chronic kidney disease.慢性肾病患者皮肤异常的前瞻性研究。
Indian J Nephrol. 2012 Mar;22(2):116-20. doi: 10.4103/0971-4065.97127.
4
Kyrle disease and acquired perforating collagenosis secondary to chronic renal failure and diabetes mellitus.Kyrle病以及继发于慢性肾衰竭和糖尿病的获得性穿通性胶原病。
Case Rep Dermatol. 2011 Sep;3(3):209-11. doi: 10.1159/000333005. Epub 2011 Sep 29.
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Kyrle's disease : a cutaneous marker of renal disorder.
Indian J Dermatol Venereol Leprol. 1996 Jul-Aug;62(4):222-5.
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Kyrle's disease and vitamin D resistant rickets in chronic renal failure (le).慢性肾衰竭中的 Kyrle 病与维生素 D 抵抗性佝偻病（le）
Indian J Dermatol Venereol Leprol. 1998 May-Jun;64(3):156.
7
Rare presentation of Kyrle's disease in siblings.Kyrle病在同胞中的罕见表现。
Indian J Dermatol. 2008;53(2):85-7. doi: 10.4103/0019-5154.41654.
8
Up-regulation of transforming growth factor-beta3 and extracellular matrix proteins in acquired reactive perforating collagenosis.获得性反应性穿通性胶原病中转化生长因子-β3和细胞外基质蛋白的上调
J Am Acad Dermatol. 2009 Mar;60(3):463-9. doi: 10.1016/j.jaad.2008.06.006.
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Perforating disorder caused by salt-water application and its experimental induction.
Int J Dermatol. 2005 Mar;44(3):210-4. doi: 10.1111/j.1365-4632.2004.01988.x.
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[Kyrle disease].[凯尔利病]
Dermatol Monatsschr. 1989;175(8):504-10.

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