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[俄罗斯临床实践中精神分裂症及精神分裂症谱系障碍的抑郁症状诊断与治疗]

[Depressive symptoms diagnosis and treatment of schizophrenia and schizophrenia spectrum disorders in Russian clinical practice].

作者信息

Gurovich I Ya, Schmukler A B, Storozhakova Ya A, Kiryanova E M, Salnikova L I, Gazha A K, Maximova N E, Stepanova O N, Suchkov Yu A

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2013;113(11 Pt 2):28-33.

Abstract

A cohort study of depression in schizophrenia and schizophrenia spectrum disorders was conducted in four Russian regional mental health services with the use of simultaneous one-day census on October 20, 2011. The total number of patients in this study was 1269: 753 patients were receiving outpatient treatment, 143 patients were served in day clinics and 373 patients were in-patients in psychiatric hospitals. Depressive symptoms were present in 6.0% of outpatients, 50.3% of day clinic patients, and 36.5% of inpatients. The average duration of current depressive symptoms in weeks was 10.0, 8.1, 9.0, respectively. The periods of depressive symptoms during the last 2 years were revealed in 30.8% of outpatients, 67.8% of day clinic patients, and 42.1% of inpatients with the average duration of each such period in weeks 10.9, 12.2, 8.3, respectively. In outpatient settings, 28.8% of patients received antidepressants in addition to antipsychotic therapy. The proportion of inpatients receiving this treatment was 42.1%, and two thirds of patients received antidepressants in day clinics.

摘要

2011年10月20日,在俄罗斯的四个地区精神卫生服务机构开展了一项关于精神分裂症及精神分裂症谱系障碍患者抑郁症的队列研究,采用了同步一日普查的方式。该研究中的患者总数为1269人:753名患者接受门诊治疗,143名患者在日间诊所接受服务,373名患者是精神病医院的住院患者。门诊患者中6.0%存在抑郁症状,日间诊所患者中50.3%存在抑郁症状,住院患者中36.5%存在抑郁症状。当前抑郁症状的平均持续时间(以周计)分别为10.0、8.1、9.0。在过去2年中,30.8%的门诊患者、67.8%的日间诊所患者和42.1%的住院患者出现过抑郁症状期,每个此类时期的平均持续时间(以周计)分别为10.9、12.2、8.3。在门诊环境中,28.8%的患者在接受抗精神病治疗的同时还服用了抗抑郁药。住院患者接受这种治疗的比例为42.1%,在日间诊所中,三分之二的患者服用了抗抑郁药。

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