胎膜早破疑似病例中阴道液乳酸水平与自然临产时间的关联。
Association between lactate levels in vaginal fluid and time of spontaneous onset of labor in suspected cases of prelabor rupture of membranes.
作者信息
Jaiswar Shyam Pyari, Natu S M, Gupta Amrit, Chaurasia Shweta
机构信息
Department of Obstetrics and Gynaecology, C S M Medical University, Lucknow, 226003 Uttar Pradesh India.
Department of Pathology, C S M Medical University, Lucknow, Uttar Pradesh India.
出版信息
J Obstet Gynaecol India. 2013 Jun;63(3):182-5. doi: 10.1007/s13224-012-0324-8. Epub 2013 Feb 22.
PURPOSE
To assess correlation between lactate levels in vaginal fluid and onset of labor in suspected PROM.
METHOD
A prospective observational study conducted at the Dept. of Obstetrics and Gynecology and Pathology from 2008 to 2009. 118 women with complaints of leaking per vaginum underwent a sterile speculum examination and vaginal fluid was taken to estimate lactate level. Then, women were followed till the spontaneous onset of labor. The association was presented as Odds ratio with 95 %CI.
RESULTS
The median time of onset of spontaneous labor and examination was 12 h in patients with lactate levels >5.0 mmol/L and 76 h in patients with lactate levels <5.0 mmol/L. Among 62 women with lactate levels >5.0 mmol/L, 67.7 % of women (n = 42) had spontaneous onset of labor within 24 h and 83.87 % women of (n = 52) within 48 h.
CONCLUSION
A lactate level >5.0 mmol/L is significantly associated with the spontaneous onset of labor within 24 and 48 h in suspected cases of PROM.
目的
评估疑似胎膜早破患者阴道液中乳酸水平与临产之间的相关性。
方法
2008年至2009年在妇产科和病理科进行了一项前瞻性观察研究。118例主诉经阴道漏液的女性接受了无菌窥器检查，并采集阴道液以评估乳酸水平。然后，对这些女性进行随访直至自然临产。相关性以比值比及95%置信区间表示。
结果
乳酸水平>5.0 mmol/L的患者自然临产与检查的中位时间为12小时，乳酸水平<5.0 mmol/L的患者为76小时。在62例乳酸水平>5.0 mmol/L的女性中，67.7%（n = 42）的女性在24小时内自然临产，83.87%（n = 52）的女性在48小时内自然临产。
结论
在疑似胎膜早破病例中，乳酸水平>5.0 mmol/L与24小时和48小时内自然临产显著相关。
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