A disseminated infection with the antifungal-multiresistant teleomorphic fungus Neocosmospora vasinfecta in a patient with acute B-lymphoblastic leukemia.

作者信息

Gabriel Frédéric, D'Almeida Mahussi, Albert Olivier, Fitton-Ouhabi Valérie, Noël Thierry, Accoceberry Isabelle

机构信息

Université de Bordeaux, Microbiologie Fondamentale et Pathogénicité UMR 5234, F-33000 Bordeaux, France ; CNRS, Microbiologie Fondamentale et Pathogénicité, UMR 5234, F-33000 Bordeaux, France ; Centre Hospitalier Universitaire de Bordeaux, Laboratoire de Parasitologie-Mycologie, F-33000 Bordeaux, France.

Université de Bordeaux, Microbiologie Fondamentale et Pathogénicité UMR 5234, F-33000 Bordeaux, France ; CNRS, Microbiologie Fondamentale et Pathogénicité, UMR 5234, F-33000 Bordeaux, France.

出版信息

Med Mycol Case Rep. 2013 Feb 9;2:44-7. doi: 10.1016/j.mmcr.2013.01.004.

DOI:10.1016/j.mmcr.2013.01.004

PMID:24432214

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3885941/

Abstract

We report on a fatal invasive infection due to the ascomycetous fungus Neocosmospora vasinfecta, in a 20-year-old European patient suffering from an acute lymphoblastic leukemia. The infection could not be controlled by a bitherapy combining liposomal amphotericin B and voriconazole. This is the second case of disseminated infection reported with this unusual fungus, which develops under its teleomorphic state, is fully resistant to all systemic antifungals, and which is known to live in tropical countries.

摘要