一名低丙种球蛋白血症患者的皮肤原藻病
Cutaneous protothecosis in a patient with hypogammaglobulinemia.
作者信息
Kwong Jason C, Ward Peter B, Johnson Paul D
机构信息
Austin Centre for Infection Research, Austin Health, Heidelberg, VIC 3084, Australia ; Department of Microbiology, Austin Health, Heidelberg, VIC 3084, Australia.
Department of Microbiology, Austin Health, Heidelberg, VIC 3084, Australia.
出版信息
Med Mycol Case Rep. 2013 Jun 20;2:132-3. doi: 10.1016/j.mmcr.2013.06.002.
Abstract
Prototheca wickerhamii has been predominantly recognised as a pathogen in immunocompromised hosts with deficits in innate or cellular immunity. The role of specific immunoglobulin against Prototheca in host immunity is uncertain. We describe a case of persistent cutaneous protothecosis in a patient with hypogammaglobulinemia most likely due to common variable immunodeficiency, with clinical response to voriconazole.
摘要
威克汉姆原藻主要被认为是先天性或细胞免疫缺陷的免疫功能低下宿主中的病原体。针对原藻的特异性免疫球蛋白在宿主免疫中的作用尚不确定。我们描述了一例可能因常见可变免疫缺陷导致低丙种球蛋白血症患者的持续性皮肤原藻病病例，该患者对伏立康唑有临床反应。
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