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犬全膀胱切除术治疗尿道及膀胱三角区移行细胞癌

Total cystectomy for treatment of transitional cell carcinoma of the urethra and bladder trigone in a dog.

作者信息

Boston Sarah, Singh Ameet

机构信息

Department of Clinical Sciences, University of Florida, Gainesville, Florida.

出版信息

Vet Surg. 2014 Mar;43(3):294-300. doi: 10.1111/j.1532-950X.2014.12104.x. Epub 2014 Jan 16.

DOI:10.1111/j.1532-950X.2014.12104.x
PMID:24433358
Abstract

OBJECTIVE

To report total cystectomy with reimplantation of the ureters in the proximal aspect of the vagina.

STUDY DESIGN

Case report.

ANIMALS

An 11-year-old female spayed Vizsla with spontaneously occurring transitional cell carcinoma of the urethra and bladder.

METHODS

After initial treatment for transitional cell carcinoma of the bladder trigone with urethral stent placement and chemotherapy, the dog developed urinary incontinence 2 months after stent placement. Eleven months after initial diagnosis, the dog developed pulmonary metastasis and local progression, leading to bilateral ureteral dilatation. After palliative radiation, total cystectomy was performed.

RESULTS

The owners elected euthanasia 442 days after original presentation and 92 days after total cystectomy. Euthanasia was unrelated to the surgical procedure, but was related to the primary disease.

CONCLUSIONS

Total cystectomy is a technically feasible procedure that should be considered for the treatment of bladder cancer in dogs.

摘要

目的

报告在阴道近端进行输尿管再植的全膀胱切除术。

研究设计

病例报告。

动物

一只11岁已绝育的维兹拉犬,患有自发性尿道和膀胱移行细胞癌。

方法

在对膀胱三角区移行细胞癌进行尿道支架置入和化疗的初始治疗后,该犬在支架置入2个月后出现尿失禁。初次诊断11个月后,该犬出现肺转移和局部进展,导致双侧输尿管扩张。在姑息性放疗后,进行了全膀胱切除术。

结果

在最初就诊442天后和全膀胱切除术后92天,主人选择实施安乐死。安乐死与手术操作无关,而是与原发性疾病有关。

结论

全膀胱切除术是一种技术上可行的手术,应考虑用于治疗犬膀胱癌。

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