Division of Neurosurgery, University Health Network, Toronto Western Hospital, University of Toronto, 399 Bathurst Street, Ontario M5T 2S8, Canada.
Division of Neurosurgery, University Health Network, Toronto Western Hospital, University of Toronto, 399 Bathurst Street, Ontario M5T 2S8, Canada.
J Clin Neurosci. 2014 Jun;21(6):927-33. doi: 10.1016/j.jocn.2013.10.015. Epub 2013 Nov 4.
The expanded endoscopic endonasal (EEE) approach for the removal of olfactory groove (OGM) and tuberculum sellae (TSM) meningiomas is currently becoming an acceptable surgical approach in neurosurgical practice, although it is still controversial with respect to its outcomes, indications and limitations. Here we provide a review of the available literature reporting results with use of the EEE approach for these lesions together with our experience with the use of the endoscope as the sole means of visualization in a series of patients with no prior surgical biopsy or resection. Surgical cases between May 2006 and January 2013 were retrospectively reviewed. Twenty-three patients (OGM n=6; TSM n=17) were identified. In our series gross total resection (GTR) was achieved in 4/6 OGM (66.7%) and 11/17 (64.7%) TSM patients. Vision improved in the OGM group (2/2) and 8/11 improved in the TSM group with no change in visual status in the remaining three patients. Post-operative cerebrospinal fluid (CSF) leak occurred in 2/6 (33%) OGM and 2/17 (11.8%) TSM patients. The literature review revealed a total of 19 OGM and 174 TSM cases which were reviewed. GTR rate was 73% for OGM and 56.3% for TSM. Post-operative CSF leak was 30% for OGM and 14% for TSM. With careful patient selection and a clear understanding of its limitations, the EEE technique is both feasible and safe. However, longer follow-ups are necessary to better define the appropriate indications and ideal patient population that will benefit from the use of these newer techniques.
扩大经鼻内镜(EEE)入路切除嗅沟(OGM)和鞍结节(TSM)脑膜瘤目前在神经外科实践中已成为一种可接受的手术方法,但对于其结果、适应证和局限性仍存在争议。在此,我们对现有的文献进行了回顾,报告了使用 EEE 入路治疗这些病变的结果,并结合我们在一系列无手术活检或切除史的患者中使用内镜作为唯一可视化手段的经验。回顾性分析了 2006 年 5 月至 2013 年 1 月的手术病例。共发现 23 例患者(OGM n=6;TSM n=17)。在我们的系列中,OGM 患者中实现了全切除(GTR)4/6(66.7%),TSM 患者中实现了 11/17(64.7%)。OGM 组中视力改善(2/2),TSM 组中 8/11 视力改善,其余 3 例视力无变化。OGM 患者中术后发生 2/6(33%)的脑脊液漏,TSM 患者中发生 2/17(11.8%)的脑脊液漏。文献回顾共回顾了 19 例 OGM 和 174 例 TSM 病例。OGM 的 GTR 率为 73%,TSM 为 56.3%。OGM 的术后脑脊液漏发生率为 30%,TSM 为 14%。通过仔细的患者选择和对其局限性的清晰认识,EEE 技术既可行又安全。然而,需要更长的随访时间来更好地确定哪些患者适合使用这些新技术,并确定哪些患者会从中受益。