Navarre Pierre, Cantin Marie-Andrée, Isler Marc H
Hôpital Sainte-Justine, Montréal, QC, Canada; Hôpital Maisonneuve-Rosemont, Montréal, QC, Canada; Université de Montréal, Montréal, QC, Canada.
Hôpital Sainte-Justine, Montréal, QC, Canada; Université de Montréal, Montréal, QC, Canada.
Int J Surg Case Rep. 2014;5(2):43-6. doi: 10.1016/j.ijscr.2013.11.002. Epub 2013 Nov 21.
Actinomycosis is known to mimic several types of neoplasms, leading to morbid surgical interventions.
We report the particular case of an extensive right para-iliac actinomycetoma presenting as a sarcoma, which to our knowledge has not yet been described in the literature, in a patient with previous ruptured appendicitis. Thanks to the collaborative work between the orthopedic and general surgeons, pathologist and microbiologist, the diagnosis of actinomycosis was made pre-operatively, saving this 15-year-old patient from a tumor resection protocol.
Actinomycetomas have often been reported to present in the same way as several abdominal and gynecological neoplasms, and on rare occasions been described as mimicking other soft-tissue sarcomas, leading to unnecessary morbid tumor resection protocols. The most common cause of abdominal actinomycosis is perforated appendicitis, and may present several years later.
While faced with a soft tissue mass transgressing tissue planes and possibly extending to the region of the right lower quadrant, especially with a history of previous perforated appendicitis, one should consider the possibility of an abscess caused by pathogens of intestinal origin, including the gram positive anaerobe Actinomycosis israelii. Failure to actively search for this pathogen, which is not detectable with routine staining techniques and may take up to 1-2 weeks to isolate, may lead to unnecessary morbid surgical procedures.
放线菌病已知可模仿多种类型的肿瘤,导致进行有害的外科手术干预。
我们报告了一例特殊病例,一名既往有阑尾炎穿孔史的患者出现广泛的右侧髂旁放线菌肿,表现为肉瘤,据我们所知,该病例在文献中尚未有描述。由于骨科医生、普通外科医生、病理学家和微生物学家的协作,术前做出了放线菌病的诊断,使这名15岁的患者免于肿瘤切除方案。
放线菌肿常被报道与多种腹部和妇科肿瘤的表现相同,少数情况下被描述为模仿其他软组织肉瘤,导致不必要的有害肿瘤切除方案。腹部放线菌病最常见的原因是阑尾炎穿孔,可能在数年后出现。
当面对一个跨越组织平面并可能延伸至右下腹区域的软组织肿块时,尤其是有既往阑尾炎穿孔史的患者,应考虑由肠道源性病原体引起脓肿的可能性,包括革兰氏阳性厌氧菌以色列放线菌。未能积极寻找这种病原体(常规染色技术无法检测到,分离可能需要长达1 - 2周时间)可能导致不必要的有害外科手术。