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腹部放线菌病的疑难诊断:一例表现为急性阑尾炎的59岁男性病例报告

Challenging Diagnosis of Abdominal Actinomycosis: A Case Report of a 59-Year-Old Male With Acute Appendicitis-Like Presentation.

作者信息

Erbagci Ahmet, Toksöz Yıldırım Ayşe Nur

机构信息

Pathology, Istanbul Medeniyet University, Istanbul, TUR.

Pathology, Göztepe Research and Training Hospital, Istanbul, TUR.

出版信息

Cureus. 2024 Oct 6;16(10):e70966. doi: 10.7759/cureus.70966. eCollection 2024 Oct.

DOI:10.7759/cureus.70966
PMID:39376974
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11456747/
Abstract

Abdominal actinomycosis, a rare and often misdiagnosed condition caused by , typically a commensal organism in the oral cavity and gastrointestinal tract, can become pathogenic, leading to chronic granulomatous infections that mimic various abdominal pathologies, including malignancies. We present a case of a 59-year-old male with coronary artery disease and type 2 diabetes who presented with severe abdominal pain, initially diagnosed as acute appendicitis. During exploratory laparotomy, an ileocecal band mimicking a congenital anomaly was discovered. Histopathological examination confirmed abdominal actinomycosis, revealing clusters of bacteria surrounded by acute inflammatory cells. The patient was successfully treated with surgical intervention and prolonged penicillin therapy, with no recurrence during a four-month follow-up. This case highlights the diagnostic challenges posed by abdominal actinomycosis and emphasizes the importance of considering it in the differential diagnosis of abdominal masses and appendicitis-like symptoms.

摘要

腹部放线菌病是一种由……引起的罕见且常被误诊的疾病,……通常是口腔和胃肠道中的共生菌,可致病,导致慢性肉芽肿性感染,其症状类似各种腹部疾病,包括恶性肿瘤。我们报告一例59岁男性病例,该患者患有冠状动脉疾病和2型糖尿病,因严重腹痛就诊,最初被诊断为急性阑尾炎。在剖腹探查术中,发现一条类似先天性异常的回盲带。组织病理学检查确诊为腹部放线菌病,显示……菌簇被急性炎症细胞包围。该患者通过手术干预和长期青霉素治疗成功治愈,在四个月的随访期间无复发。本病例突出了腹部放线菌病所带来的诊断挑战,并强调了在腹部肿块和类似阑尾炎症状的鉴别诊断中考虑该病的重要性。 (注:原文中部分关键信息缺失,用“……”代替)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d43e/11456747/8aef9aa382c1/cureus-0016-00000070966-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d43e/11456747/eba576b0a4e4/cureus-0016-00000070966-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d43e/11456747/e8b8259f4795/cureus-0016-00000070966-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d43e/11456747/525a3709a2b0/cureus-0016-00000070966-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d43e/11456747/8aef9aa382c1/cureus-0016-00000070966-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d43e/11456747/eba576b0a4e4/cureus-0016-00000070966-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d43e/11456747/e8b8259f4795/cureus-0016-00000070966-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d43e/11456747/525a3709a2b0/cureus-0016-00000070966-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d43e/11456747/8aef9aa382c1/cureus-0016-00000070966-i04.jpg

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本文引用的文献

1
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2
Abdominal actinomycosis mimicking a transverse colon malignancy: a case report and review of the literature.酷似横结肠癌的腹部放线菌病:一例报告并文献复习
J Med Case Rep. 2021 May 3;15(1):224. doi: 10.1186/s13256-021-02812-7.
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Abdominal actinomycosis.腹部放线菌病
Int J Surg. 2007 Dec;5(6):441-8. doi: 10.1016/j.ijsu.2006.06.009. Epub 2006 Aug 10.
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A rare case of ascending colon actinomycosis mimicking cancer.一例罕见的酷似癌症的升结肠放线菌病。
BMC Gastroenterol. 2005 Jan 4;5:1. doi: 10.1186/1471-230X-5-1.
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Radiology. 2001 Jul;220(1):76-80. doi: 10.1148/radiology.220.1.r01jl1376.
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Pelvic actinomycosis. Is long-term antibiotic therapy necessary?盆腔放线菌病。长期抗生素治疗有必要吗?
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Actinomycosis.放线菌病
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Abdominal actinomycosis.腹部放线菌病
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