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迷走神经诱导的胃窦收缩及液体试验餐的胃排空

Vagally induced gastric antral contractions and gastric emptying of a liquid test meal.

作者信息

Carr D H, Brooks F P

出版信息

Q J Exp Physiol Cogn Med Sci. 1978 Jan;63(1):49-58. doi: 10.1113/expphysiol.1978.sp002414.

DOI:10.1113/expphysiol.1978.sp002414
PMID:244362
Abstract

The emptying of a liquid test meal from the stomach was studied during, and in the absence of, electrical stimulation of cut ends of a thoracic branch of the vagus in anaesthetized cats. The test meal (154 mmol.1-1 NaCl and 30 mg.1-1 phenol red) was measured by collecting effluent from a duodenal fistula over a 30 min period. The stomach emptied about 60% of the meal under control conditions compared with over 90% during efferent stimulation of the vagus. The increased volumes emptied during efferent stimulation were not accounted for by secretion of gastric acid. Coincident with the vagally evoked antral contractions there was a gush of liquid from the duodenal cannula. Afferent vagal stimulation resulted in an initial marked delay of emptying followed by an acceleration so that the volume emptied after 30 min was similar to that in control experiments. Antral contractions, evoked by efferent vagal stimulation, accelerated the emptying of a liquid test meal from the stomach.

摘要

在麻醉猫身上,研究了迷走神经胸部分支切断端在接受电刺激期间及无电刺激时液体试验餐从胃中的排空情况。试验餐(154 mmol·L⁻¹氯化钠和30 mg·L⁻¹酚红)通过在30分钟内收集十二指肠瘘的流出物来测量。在对照条件下,胃排空约60%的试验餐,而在迷走神经传出刺激期间,这一比例超过90%。传出刺激期间排空量增加并非由胃酸分泌所致。与迷走神经诱发的胃窦收缩同时发生的是,十二指肠插管中有一股液体涌出。传入迷走神经刺激导致排空最初明显延迟,随后加速,因此30分钟后排空的量与对照实验中的相似。迷走神经传出刺激诱发的胃窦收缩加速了液体试验餐从胃中的排空。

相似文献

1
Vagally induced gastric antral contractions and gastric emptying of a liquid test meal.迷走神经诱导的胃窦收缩及液体试验餐的胃排空
Q J Exp Physiol Cogn Med Sci. 1978 Jan;63(1):49-58. doi: 10.1113/expphysiol.1978.sp002414.
2
Proceedings: Electrical vagal-induced gastric antral contractions and gastric emptying of a liquid test meal in anaesthetized cats.
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The gastric motility patterns induced by direct and reflex excitation of the vagus nerves in the anaesthetized ferret.
麻醉雪貂中迷走神经直接和反射性兴奋所诱导的胃运动模式。
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The lateral decubitus position may affect gastric emptying through an autonomic mechanism: the skin pressure-vegetative reflex.侧卧位可能通过自主神经机制——皮肤压力-自主神经反射来影响胃排空。
Br J Clin Pharmacol. 1991 Jul;32(1):138-9. doi: 10.1111/j.1365-2125.1991.tb05631.x.