雪貂胃扩张引起的胃窦运动反射性兴奋。
Reflex excitation of antral motility induced by gastric distension in the ferret.
作者信息
Andrews P L, Grundy D, Scratcherd T
出版信息
J Physiol. 1980 Jan;298:79-84. doi: 10.1113/jphysiol.1980.sp013068.
Abstract
- In the urethane anaesthetized ferret gastric inflation with 50 ml. 0.9% NaCl at a rate of 10 ml./min evoked large gastric contractions. The threshold of intragastric pressure required to elicit the reflex was 3.1 +/- 0.5 cmH2O. 2. The response was enhanced by splanchnic nerve section and markedly reduced by bilateral cervical vagotomy, indicating that both afferent and efferent limbs of the reflex were in the vagus nerves. 3. By using a transected stomach it was shown that distension of the corpus evoked contractions of the antrum that were abolished by vagotomy. 4. The reflex activation of antral motility by vagal afferents with receptive fields in the corpus may play a physiological role in gastric emptying.
摘要
- 在氨基甲酸乙酯麻醉的雪貂中，以10毫升/分钟的速度用50毫升0.9%氯化钠进行胃扩张可诱发强烈的胃收缩。引发该反射所需的胃内压阈值为3.1±0.5厘米水柱。2. 内脏神经切断可增强该反应，双侧颈迷走神经切断则使其明显减弱，这表明该反射的传入和传出支均在迷走神经中。3. 通过使用横断的胃，发现胃体扩张可诱发胃窦收缩，而迷走神经切断可消除这种收缩。4. 胃体中具有感受野的迷走神经传入纤维对胃窦运动的反射性激活可能在胃排空过程中发挥生理作用。
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