尿素输注对饲喂低蛋白和高蛋白日粮绵羊的肾小球滤过率及肾血浆流量的影响。
The effects of urea infusion on glomerular filtration rate and renal plasma flow in sheep fed low and high protein diets.
作者信息
Ergene N, Pickering E C
出版信息
Q J Exp Physiol Cogn Med Sci. 1978 Jan;63(1):77-81. doi: 10.1113/expphysiol.1978.sp002417.
Reducing the dietary N intake of sheep resulted in a significant fall in GFR with no change in RPF. Intravenous of urea for 19-46 h had no effect on the high protein diet but on the low protein diet GFR and FF were increased to values approaching those observed on the high protein diet. On the low protein diet GFR was unaffected by infusion of urea for 4 h or of saline alone for 30 h. It is suggested that the observed changes in GFR are associated with changes in the quantity of protein passing to the abomasum and small intestine.
减少绵羊的日粮氮摄入量会导致肾小球滤过率（GFR）显著下降，而肾血浆流量（RPF）无变化。静脉注射尿素19 - 46小时对高蛋白日粮无影响，但对低蛋白日粮而言，肾小球滤过率和滤过分数（FF）增加至接近高蛋白日粮时观察到的值。在低蛋白日粮情况下，静脉注射尿素4小时或单独注射生理盐水30小时对肾小球滤过率无影响。有人认为，观察到的肾小球滤过率变化与进入皱胃和小肠的蛋白质量变化有关。
Zotero 插件