Phua C K, Chadachan V M, Acharya R
Department of General Medicine, Tan Tock Seng Hospital, Tan Tock Seng, Singapore.
Int J Angiol. 2013 Jun;22(2):137-42. doi: 10.1055/s-0033-1336828.
Lemierre syndrome is an uncommon condition classically described in acute oropharyngeal infection with septic thrombophlebitis of the internal jugular vein and metastatic septic embolism particularly to the lungs. It is commonly described in young healthy adults with isolation of Fusobacterium necrophorum. We describe a case of Lemierre syndrome in a 50-year-old man with newly diagnosed diabetes mellitus presenting with a neck abscess secondary to Klebsiella pneumoniae. Our patient made good recovery to appropriate antimicrobial therapy, prompt surgical drainage, and anticoagulation. Anticoagulation remains controversial and we review the literature for its role in Lemierre syndrome.
勒米尔综合征是一种罕见病症，典型表现为急性口咽感染伴颈内静脉化脓性血栓性静脉炎及转移性化脓性栓塞，尤其是肺部栓塞。该病常见于分离出坏死梭杆菌的年轻健康成年人。我们报告一例50岁男性勒米尔综合征病例，该患者新诊断为糖尿病，因肺炎克雷伯菌感染继发颈部脓肿。我们的患者通过适当的抗菌治疗、及时的手术引流和抗凝治疗后恢复良好。抗凝治疗仍存在争议，我们回顾了相关文献以探讨其在勒米尔综合征中的作用。
