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勒米尔综合征——我们应该进行抗凝治疗吗?一例病例报告及文献综述。

Lemierre syndrome-should we anticoagulate? A case report and review of the literature.

作者信息

Phua C K, Chadachan V M, Acharya R

机构信息

Department of General Medicine, Tan Tock Seng Hospital, Tan Tock Seng, Singapore.

出版信息

Int J Angiol. 2013 Jun;22(2):137-42. doi: 10.1055/s-0033-1336828.

Abstract

Lemierre syndrome is an uncommon condition classically described in acute oropharyngeal infection with septic thrombophlebitis of the internal jugular vein and metastatic septic embolism particularly to the lungs. It is commonly described in young healthy adults with isolation of Fusobacterium necrophorum. We describe a case of Lemierre syndrome in a 50-year-old man with newly diagnosed diabetes mellitus presenting with a neck abscess secondary to Klebsiella pneumoniae. Our patient made good recovery to appropriate antimicrobial therapy, prompt surgical drainage, and anticoagulation. Anticoagulation remains controversial and we review the literature for its role in Lemierre syndrome.

摘要

勒米尔综合征是一种罕见病症,典型表现为急性口咽感染伴颈内静脉化脓性血栓性静脉炎及转移性化脓性栓塞,尤其是肺部栓塞。该病常见于分离出坏死梭杆菌的年轻健康成年人。我们报告一例50岁男性勒米尔综合征病例,该患者新诊断为糖尿病,因肺炎克雷伯菌感染继发颈部脓肿。我们的患者通过适当的抗菌治疗、及时的手术引流和抗凝治疗后恢复良好。抗凝治疗仍存在争议,我们回顾了相关文献以探讨其在勒米尔综合征中的作用。

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[A case of Lemierre syndrome].[一例勒米尔综合征病例]
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本文引用的文献

1
Lemierre syndrome.勒米尔综合征
Med J Malaysia. 2012 Jun;67(3):340-1.
2
A Lemierre syndrome variant caused by Klebsiella pneumoniae.由肺炎克雷伯菌引起的李孟杰尔综合征变异型。
J Formos Med Assoc. 2012 Jul;111(7):403-5. doi: 10.1016/j.jfma.2012.03.012. Epub 2012 Apr 8.
9
10
Lemierre syndrome: a pediatric case series and review of literature.勒米厄尔综合征:儿科病例系列及文献复习。
Am J Otolaryngol. 2010 Jan-Feb;31(1):38-45. doi: 10.1016/j.amjoto.2008.09.006. Epub 2009 Mar 26.

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