促进结直肠手术后肠道功能恢复：阿片受体拮抗剂和咀嚼口香糖。
Facilitating return of bowel function after colorectal surgery: alvimopan and gum chewing.
作者信息
Keller Deborah, Stein Sharon L
机构信息
Division of Colorectal Surgery, Department of Surgery, University Hospitals Case Medical Center, Cleveland, Ohio.
出版信息
Clin Colon Rectal Surg. 2013 Sep;26(3):186-90. doi: 10.1055/s-0033-1351137.
Abstract
Postoperative ileus is common after colorectal surgery, and has a huge impact on hospital LOS. With the impeding cost crisis in the United States, safely reducing length of stay is essential. Chewing gum and pharmacological treatment with alvimopan are safe, simple tools to reduce postoperative ileus and its associated costs. Future research will determine if integrating these tools with laparoscopic procedures and enhanced recovery pathways is a best practice in colorectal surgery.
摘要
结直肠手术后肠梗阻很常见，且对住院时间有巨大影响。鉴于美国日益严峻的成本危机，安全缩短住院时间至关重要。嚼口香糖和使用爱维莫潘进行药物治疗是安全、简便的减少术后肠梗阻及其相关成本的方法。未来的研究将确定将这些方法与腹腔镜手术及强化康复方案相结合是否为结直肠手术的最佳实践。
相似文献
1
Facilitating return of bowel function after colorectal surgery: alvimopan and gum chewing.促进结直肠手术后肠道功能恢复：阿片受体拮抗剂和咀嚼口香糖。
Clin Colon Rectal Surg. 2013 Sep;26(3):186-90. doi: 10.1055/s-0033-1351137.
2
Alvimopan Provides Additional Improvement in Outcomes and Cost Savings in Enhanced Recovery Colorectal Surgery.爱维莫潘在加速康复结直肠手术中可进一步改善预后并节省成本。
Ann Surg. 2016 Jul;264(1):141-6. doi: 10.1097/SLA.0000000000001428.
3
Pharmacologic options to prevent postoperative ileus.预防术后肠梗阻的药理学选择。
Ann Pharmacother. 2009 Sep;43(9):1474-85. doi: 10.1345/aph.1M121. Epub 2009 Jul 14.
4
Usefulness of Gum Chewing to Decrease Postoperative Ileus in Colorectal Surgery with Primary Anastomosis: A Randomized Controlled Trial.咀嚼口香糖对减少结直肠一期吻合手术术后肠梗阻的作用：一项随机对照试验
Rev Invest Clin. 2016 Nov-Dec;68(6):314-318.
5
Effect of gum chewing on ameliorating ileus following colorectal surgery: A meta-analysis of 18 randomized controlled trials.咀嚼口香糖对改善结直肠手术后肠麻痹的效果：18 项随机对照试验的荟萃分析。
Int J Surg. 2017 Nov;47:107-115. doi: 10.1016/j.ijsu.2017.07.107. Epub 2017 Sep 1.
6
Sham feeding with chewing gum after elective colorectal resectional surgery: a randomized clinical trial.择期结直肠切除术后咀嚼口香糖行假饲：一项随机临床试验。
Ann Surg. 2013 Jun;257(6):1016-24. doi: 10.1097/SLA.0b013e318286504a.
7
Multicentre randomized clinical trial of the effect of chewing gum after abdominal surgery.腹部手术后咀嚼口香糖的效果：多中心随机临床试验。
Br J Surg. 2018 Jun;105(7):820-828. doi: 10.1002/bjs.10828. Epub 2018 Feb 22.
8
Is there value in alvimopan in minimally invasive colorectal surgery?爱维莫潘在微创结直肠手术中有价值吗？
Am J Surg. 2016 Nov;212(5):851-856. doi: 10.1016/j.amjsurg.2016.02.016. Epub 2016 May 10.
9
Alvimopan in the setting of colorectal resection with an ostomy: To use or not to use?结直肠切除并造口术后应用阿片激动拮抗剂：用还是不用？
Surg Endosc. 2017 Sep;31(9):3483-3488. doi: 10.1007/s00464-016-5373-0. Epub 2016 Dec 7.
10
Health-related quality of life and cost-effectiveness analysis of gum chewing in patients undergoing colorectal surgery: results of a randomized controlled trial.结直肠手术患者咀嚼口香糖的健康相关生活质量及成本效益分析：一项随机对照试验的结果
Acta Chir Belg. 2018 Oct;118(5):299-306. doi: 10.1080/00015458.2018.1432742. Epub 2018 Jan 30.
引用本文的文献
1
Erector Spinae Plane Block versus Quadratus Lumborum Block for Postoperative Analgesia after Laparoscopic Resection of Colorectal Cancer: A Prospective Randomized Study.竖脊肌平面阻滞与腰方肌阻滞用于腹腔镜结直肠癌切除术后镇痛的前瞻性随机研究
Anesthesiol Res Pract. 2024 Mar 18;2024:6200915. doi: 10.1155/2024/6200915. eCollection 2024.
2
Analgesic efficacy of the bilateral erector spinae plane block for colorectal surgery: a randomized controlled trial.双侧竖脊肌平面阻滞用于结直肠手术的镇痛效果：一项随机对照试验
J Anesth Analg Crit Care. 2022 Oct 21;2(1):43. doi: 10.1186/s44158-022-00073-4.
3
The impact of low-pressure pneumoperitoneum on robotic-assisted radical cystectomy and intracorporeal ileal conduit urinary diversion: a case-control study.低压气腹对机器人辅助根治性膀胱切除术和腔内置入回肠导管尿流改道术的影响：一项病例对照研究。
World J Urol. 2022 Oct;40(10):2467-2472. doi: 10.1007/s00345-022-04117-w. Epub 2022 Sep 5.
4
Outcomes of Alvimopan Use in Laparoscopic Intra-abdominal Surgery: A Retrospective Review.阿维莫潘用于腹腔镜腹部手术的疗效：一项回顾性研究
Innov Pharm. 2021 Sep 22;12(4). doi: 10.24926/iip.v12i4.3969. eCollection 2021.
5
Abilities of Pre-Treatment Inflammation Ratios as Classification or Prediction Models for Patients with Colorectal Cancer.治疗前炎症比值作为结直肠癌患者分类或预测模型的能力。
Diagnostics (Basel). 2021 Mar 21;11(3):566. doi: 10.3390/diagnostics11030566.
6
Comparing the safety, efficacy, and oncological outcomes of laparoscopic and open colectomy in transverse colon cancer: a meta-analysis.比较腹腔镜与开腹结肠切除术治疗横结肠癌的安全性、有效性及肿瘤学结局：一项荟萃分析
Int J Colorectal Dis. 2020 Mar;35(3):373-386. doi: 10.1007/s00384-020-03516-y. Epub 2020 Jan 24.
7
A randomized controlled trial comparing early versus late oral feeding after cesarean section under regional anesthesia.一项在区域麻醉下剖宫产术后比较早期与晚期经口喂养的随机对照试验。
Int J Womens Health. 2019 Sep 13;11:519-525. doi: 10.2147/IJWH.S222922. eCollection 2019.
8
Newly implemented enhanced recovery pathway positively impacts hospital length of stay.新实施的强化康复路径对住院时间产生积极影响。
Surg Endosc. 2016 Sep;30(9):4019-28. doi: 10.1007/s00464-015-4714-8. Epub 2015 Dec 22.
9
Does alvimopan enhance return of bowel function in laparoscopic gastrointestinal surgery? A meta-analysis.阿维莫潘能否促进腹腔镜胃肠手术中肠功能的恢复？一项荟萃分析。
Ann Gastroenterol. 2015 Oct-Dec;28(4):475-80.
本文引用的文献
1
A prospective randomized controlled trial of sugared chewing gum on gastrointestinal recovery after major colorectal surgery in patients managed with early enteral feeding.一项关于含糖口香糖对早期肠内喂养管理的结直肠手术后胃肠功能恢复影响的前瞻性随机对照试验。
Dis Colon Rectum. 2013 Mar;56(3):328-35. doi: 10.1097/DCR.0b013e31827e4971.
2
Gum in the postoperative setting: something to chew on.
Dis Colon Rectum. 2013 Mar;56(3):273-4. doi: 10.1097/DCR.0b013e31827d1605.
3
Stimulation of the autonomic nervous system in colorectal surgery: a study protocol for a randomized controlled trial.刺激结直肠手术中的自主神经系统：一项随机对照试验的研究方案。
Trials. 2012 Jun 27;13:93. doi: 10.1186/1745-6215-13-93.
4
Alvimopan addition to a standard perioperative recovery pathway.在标准围手术期恢复路径中添加阿维莫潘。
JSLS. 2011 Oct-Dec;15(4):492-8. doi: 10.4293/108680811X13176785204076.
5
Real world efficacy of alvimopan on elective bowel resection patients: an analysis of statistical versus clinical significance.在择期肠切除患者中 alvimopan 的真实世界疗效：统计与临床意义分析。
Am J Surg. 2012 Mar;203(3):308-11; discussion 311-2. doi: 10.1016/j.amjsurg.2011.09.007. Epub 2011 Dec 16.
6
Gum chewing during pre-anesthetic fasting.麻醉前禁食期间咀嚼口香糖。
Paediatr Anaesth. 2012 Mar;22(3):288-96. doi: 10.1111/j.1460-9592.2011.03751.x. Epub 2011 Dec 15.
7
Introduction of alvimopan into an enhanced recovery protocol for colectomy offers benefit in open but not laparoscopic colectomy.将阿维莫潘引入结肠切除术的强化康复方案中，在开放手术的结肠切除术中有益，但在腹腔镜结肠切除术中则不然。
J Laparoendosc Adv Surg Tech A. 2011 Dec;21(10):887-91. doi: 10.1089/lap.2011.0209. Epub 2011 Sep 22.
8
A characterization of factors determining postoperative ileus after laparoscopic colectomy enables the generation of a novel predictive score.对腹腔镜结肠切除术术后肠麻痹相关因素的特征分析有助于生成一种新的预测评分。
Ann Surg. 2011 Jan;253(1):78-81. doi: 10.1097/SLA.0b013e3181fcb83e.
9
[Usefulness of chewing gum for the resolution of postoperative ileus in left colon resections].
Rev Gastroenterol Mex. 2010 Oct-Dec;75(4):369-73.
10
Alvimopan use in laparoscopic and open bowel resections: clinical results in a large community hospital system.阿维莫潘在腹腔镜和开放性肠切除术中的应用：大型社区医院系统的临床结果。
Ann Pharmacother. 2010 Nov;44(11):1701-8. doi: 10.1345/aph.1P260. Epub 2010 Sep 21.
Zotero 插件